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L L Brunton

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Articles 74
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21.
Urasawa K, Brunton L
J Biol Chem . 1992 May; 267(15):10620-4. PMID: 1316904
We have assessed the effects of endothelin-1 (ET-1) on transmembrane signaling in adult rat ventricular myocytes. ET-1 stimulates phosphoinositide hydrolysis with an EC50 of 0.3-0.8 nM. This stimulation is linear...
22.
McMahan C, Slack J, Mosley B, Cosman D, Lupton S, Brunton L, et al.
EMBO J . 1991 Oct; 10(10):2821-32. PMID: 1833184
cDNA clones corresponding to an Mr approximately 80,000 receptor (type I receptor) for interleukin-1 (IL-1) have been isolated previously by mammalian expression. Here, we report the use of an improved...
23.
Speizer L, Watson M, Brunton L
Am J Physiol . 1991 Jul; 261(1 Pt 1):E109-14. PMID: 1858866
We studied the in vitro effects of omega-3 fish oils and other fatty acids on the activity of crude protein kinase C from S49 lymphoma cells, on partially purified enzyme...
24.
Lupton S, Brunton L, KALBERG V, Overell R
Mol Cell Biol . 1991 Jun; 11(6):3374-8. PMID: 1645450
The hygromycin phosphotransferase gene was fused in-frame with the herpes simplex virus type 1 thymidine kinase gene. The resulting fusion gene (termed HyTK) confers hygromycin B resistance for dominant positive...
25.
Bode D, Kanter J, Brunton L
Circ Res . 1991 Apr; 68(4):1070-9. PMID: 1849058
We have resolved multiple forms of cyclic nucleotide phosphodiesterase (PDE) in whole rat ventricle and in isolated rat ventricular myocytes by use of anion-exchange high-performance liquid chromatography. One major form,...
26.
Heidenreich K, Toledo S, Brunton L, Watson M, Daniel-Issakani S, Strulovici B
J Biol Chem . 1990 Sep; 265(25):15076-82. PMID: 2203768
In this study we examined the effects of insulin on protein kinase C (PKC) activity in cultured fetal chick neurons. PKC activity, measured as 32P incorporation into histone H1 in...
27.
Goodman M, Speizer L, Bokoch G, Kanter J, Brunton L
J Biol Chem . 1990 Jul; 265(21):12248-52. PMID: 2165055
We have evaluated potential molecular mechanisms by which a group of synthetic lymphokine-like molecules, the 7,8-disubstituted guanine ribonucleosides, acts on second messenger pathways to augment the responses of murine B...
28.
Lupton S, Gimpel S, Jerzy R, Brunton L, Hjerrild K, Cosman D, et al.
J Immunol . 1990 May; 144(9):3592-601. PMID: 2329282
IL-7 cDNA clones were used to isolate clones from the human IL-7 gene locus. Characterization of the clones revealed that the human IL-7 gene contains six exons, distributed over more...
29.
Bell J, Biltonen R, Brunton L
Mol Pharmacol . 1990 Apr; 37(4):535-45. PMID: 2109182
The time course of cAMP production by S49 cell membranes in the presence of forskolin and a nonhydrolyzable GTP analog can yield information about the regulation of adenylate cyclase by...
30.
Brunton L, Lupton S
Nucleic Acids Res . 1990 Mar; 18(5):1315. PMID: 2320434
No abstract available.