L Karl Olson
Overview
Explore the profile of L Karl Olson including associated specialties, affiliations and a list of published articles.
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24
Citations
940
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Recent Articles
1.
Marcus Post L, Pathak D, Hamilton A, Hirko K, Houang R, Guseman E, et al.
Cancer Epidemiol Biomarkers Prev
. 2024 Oct;
33(12):1659-1670.
PMID: 39356300
Background: The role of adult adiposity in young-onset breast cancer (YOBC) subtype risk is not well understood. Methods: In this population-based case (n = 1812)-control (n = 1,381) study of...
2.
Sotzen M, Ahmed A, Olson L, Alshaarawy O
Front Endocrinol (Lausanne)
. 2024 Jul;
15:1386230.
PMID: 38962676
Background: Despite the evidence that energy balance is regulated differently in females and that the endocannabinoid system is sexually dimorphic, previous studies on the endocannabinoid system and energy balance predominantly...
3.
Velie E, Marcus L, Pathak D, Hamilton A, DiGaetano R, Klinger R, et al.
Cancer Causes Control
. 2021 Jul;
32(10):1129-1148.
PMID: 34292440
Purpose: The etiology of young-onset breast cancer (BC) is poorly understood, despite its greater likelihood of being hormone receptor-negative with a worse prognosis and persistent racial and socioeconomic inequities. We...
4.
Truong N, Lydic T, Bazil J, Suryadevara A, Olson L
Cytokine
. 2020 Jun;
133:155147.
PMID: 32492632
Interferons (IFN) have been shown to alter lipid metabolism in immune and some non-hematopoietic cells and this affects host cell response to pathogens. In type 1 diabetes, IFNγ acts as...
5.
Wang P, Liu Q, Zhao H, Bishop J, Zhou G, Olson L, et al.
Sci Rep
. 2020 Mar;
10(1):5302.
PMID: 32210316
Aberrant expression of miRNAs in pancreatic islets is closely related to the development of type 1 diabetes (T1D). The aim of this study was to identify key miRNAs dysregulated in...
6.
Alshaarawy O, Kurjan E, Truong N, Olson L
Obesity (Silver Spring)
. 2019 Jan;
27(3):454-461.
PMID: 30699233
Objective: Evidence suggests that cannabinoid-1 receptor (CB1R) activation is associated with increased food intake and body weight gain. Human epidemiological studies, however, show decreased prevalence of obesity in cannabis users....
7.
Cai Y, Lydic T, Turkette T, Reid G, Olson L
Biochem Pharmacol
. 2015 Mar;
95(1):46-57.
PMID: 25801003
Prolonged exposure of pancreatic beta (β) cells to elevated glucose and free fatty acids (FFA) as occurs in type 2 diabetes results in loss of β cell function and survival....
8.
Baldwin A, Green C, Olson L, Moxley M, Corbett J
Am J Physiol Endocrinol Metab
. 2012 Mar;
302(11):E1390-8.
PMID: 22436701
Exposure of insulin-producing cells to elevated levels of the free fatty acid (FFA) palmitate results in the loss of β-cell function and induction of apoptosis. The induction of endoplasmic reticulum...
9.
Green C, Olson L
Am J Physiol Endocrinol Metab
. 2011 Jan;
300(4):E640-9.
PMID: 21266672
Induction of endoplasmic reticulum (ER) stress and apoptosis by elevated exogenous saturated fatty acids (FAs) plays a role in the pathogenesis of β-cell dysfunction and loss of islet mass in...
10.
Jump D, Torres-Gonzalez M, Olson L
Biochem Pharmacol
. 2010 Dec;
81(5):649-60.
PMID: 21184748
Acetyl CoA carboxylase (ACC1 and ACC2) generates malonyl CoA, a substrate for de novo lipogenesis (DNL) and an inhibitor of mitochondrial fatty acid β-oxidation (FAO). Malonyl CoA is also a...