L I Golbe
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Explore the profile of L I Golbe including associated specialties, affiliations and a list of published articles.
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71
Citations
5014
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Recent Articles
1.
Tobin J, Latourelle J, Lew M, Klein C, Suchowersky O, Shill H, et al.
Neurology
. 2008 May;
71(1):28-34.
PMID: 18509094
Background: Microtubule-associated protein tau (MAPT) has been associated with several neurodegenerative disorders including forms of parkinsonism and Parkinson disease (PD). We evaluated the association of the MAPT region with PD...
2.
Wilk J, Tobin J, Suchowersky O, Shill H, Klein C, Wooten G, et al.
Neurology
. 2006 Dec;
67(12):2206-10.
PMID: 17190945
Background: Polymorphisms in the glutathione S-transferase pi gene (GSTP1), encoding GSTP1-1, a detoxification enzyme, may increase the risk of Parkinson disease (PD) with exposure to pesticides. Using the GenePD Study...
3.
Karamohamed S, Latourelle J, Racette B, Perlmutter J, Wooten G, Lew M, et al.
Neurology
. 2005 Dec;
65(11):1823-5.
PMID: 16344533
Brain-derived neurotrophic factor (BDNF) stimulates neuronal growth and protects nigral dopamine neurons in animal models of Parkinson disease (PD). Therefore, BDNF is a candidate gene for PD. The authors investigated...
4.
Karamohamed S, Golbe L, Mark M, Lazzarini A, Suchowersky O, Labelle N, et al.
Mov Disord
. 2005 Jun;
20(9):1188-91.
PMID: 15966003
Parkinson's disease (PD) is a neurodegenerative disorder in which relatives of the probands are affected approximately 4 times as frequently as relatives of control subjects. Several genes have been implicated...
5.
Karamohamed S, DeStefano A, Wilk J, Shoemaker C, Golbe L, Mark M, et al.
Neurology
. 2003 Dec;
61(11):1557-61.
PMID: 14663042
Objective: To identify a haplotype influencing onset age for Parkinson's disease (PD) in the PARK3 region on chromosome 2p13. Methods: Single nucleotide polymorphisms (SNP) spanning 2.2 Mb and located in...
6.
Maher N, Currie L, Lazzarini A, Wilk J, Taylor C, Saint-Hilaire M, et al.
Am J Med Genet
. 2002 Apr;
109(3):191-7.
PMID: 11977177
The role of genetics in Parkinson disease (PD) continues to be an area of considerable interest and controversy. We collected information involving the nuclear families of 948 consecutively ascertained PD...
7.
Maher N, Golbe L, Lazzarini A, Mark M, Currie L, Wooten G, et al.
Neurology
. 2002 Jan;
58(1):79-84.
PMID: 11781409
Objective: To examine patterns of familial aggregation and factors influencing onset age in a sample of siblings with PD. Methods: Sibling pairs (n = 203) with PD were collected as...
8.
DeStefano A, Golbe L, Mark M, Lazzarini A, Maher N, Saint-Hilaire M, et al.
Neurology
. 2001 Sep;
57(6):1124-6.
PMID: 11571351
A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214 cM, lod = 1.20),...
9.
Golbe L, Lazzarini A, Spychala J, Johnson W, Stenroos E, Mark M, et al.
Mov Disord
. 2001 Jun;
16(3):442-7.
PMID: 11391737
Parkinson's disease (PD) is primarily an alpha-synucleinopathy, rather than a tauopathy, but there is evidence for an indirect association of tau with the pathogenetic process in PD. We therefore assessed...
10.
Swerdlow R, Parks J, Cassarino D, Binder D, Bennett Jr J, Di Iorio G, et al.
Exp Neurol
. 2001 May;
169(2):479-85.
PMID: 11358461
Complex I activity is reduced in cytoplasmic hybrid (cybrid) cell lines that contain mitochondrial DNA (mtDNA) from sporadic Parkinson's disease (PD) patients. This implies that mtDNA aberration occurs in sporadic...