A M Lazzarini
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Explore the profile of A M Lazzarini including associated specialties, affiliations and a list of published articles.
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15
Citations
3381
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Recent Articles
1.
Karamohamed S, Golbe L, Mark M, Lazzarini A, Suchowersky O, Labelle N, et al.
Mov Disord
. 2005 Jun;
20(9):1188-91.
PMID: 15966003
Parkinson's disease (PD) is a neurodegenerative disorder in which relatives of the probands are affected approximately 4 times as frequently as relatives of control subjects. Several genes have been implicated...
2.
Karamohamed S, DeStefano A, Wilk J, Shoemaker C, Golbe L, Mark M, et al.
Neurology
. 2003 Dec;
61(11):1557-61.
PMID: 14663042
Objective: To identify a haplotype influencing onset age for Parkinson's disease (PD) in the PARK3 region on chromosome 2p13. Methods: Single nucleotide polymorphisms (SNP) spanning 2.2 Mb and located in...
3.
Maher N, Currie L, Lazzarini A, Wilk J, Taylor C, Saint-Hilaire M, et al.
Am J Med Genet
. 2002 Apr;
109(3):191-7.
PMID: 11977177
The role of genetics in Parkinson disease (PD) continues to be an area of considerable interest and controversy. We collected information involving the nuclear families of 948 consecutively ascertained PD...
4.
Maher N, Golbe L, Lazzarini A, Mark M, Currie L, Wooten G, et al.
Neurology
. 2002 Jan;
58(1):79-84.
PMID: 11781409
Objective: To examine patterns of familial aggregation and factors influencing onset age in a sample of siblings with PD. Methods: Sibling pairs (n = 203) with PD were collected as...
5.
DeStefano A, Golbe L, Mark M, Lazzarini A, Maher N, Saint-Hilaire M, et al.
Neurology
. 2001 Sep;
57(6):1124-6.
PMID: 11571351
A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214 cM, lod = 1.20),...
6.
Golbe L, Lazzarini A, Spychala J, Johnson W, Stenroos E, Mark M, et al.
Mov Disord
. 2001 Jun;
16(3):442-7.
PMID: 11391737
Parkinson's disease (PD) is primarily an alpha-synucleinopathy, rather than a tauopathy, but there is evidence for an indirect association of tau with the pathogenetic process in PD. We therefore assessed...
7.
Compound heterozygous genotype is associated with protracted juvenile neuronal ceroid lipofuscinosis
Wisniewski K, Zhong N, Kaczmarski W, Kaczmarski A, Kida E, Brown W, et al.
Ann Neurol
. 1998 Feb;
43(1):106-10.
PMID: 9450775
We present a clinicopathological study and the first molecular genetic analysis of a family with 2 siblings affected by a rare, protracted form of juvenile neuronal ceroid lipofuscinosis (JNCL). Molecular...
8.
Polymeropoulos M, Lavedan C, Leroy E, Ide S, Dehejia A, Dutra A, et al.
Science
. 1997 Jun;
276(5321):2045-7.
PMID: 9197268
Parkinson's disease (PD) is a common neurodegenerative disorder with a lifetime incidence of approximately 2 percent. A pattern of familial aggregation has been documented for the disorder, and it was...
9.
Polymeropoulos M, Higgins J, Golbe L, Johnson W, Ide S, Di Iorio G, et al.
Science
. 1996 Nov;
274(5290):1197-9.
PMID: 8895469
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, affecting approximately 1 percent of the population over age 50. Recent studies have confirmed significant familial aggregation...
10.
Golbe L, Di Iorio G, Sanges G, Lazzarini A, La Sala S, Bonavita V, et al.
Ann Neurol
. 1996 Nov;
40(5):767-75.
PMID: 8957018
We performed a clinical genetic analysis of a kindred originating in the town of Contursi in Salerno province, Italy, in which 60 individuals in 5 generations are known to have...