L G Guidotti
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Explore the profile of L G Guidotti including associated specialties, affiliations and a list of published articles.
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3723
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Recent Articles
1.
Ricciardi S, Miluzio A, Brina D, Clarke K, Bonomo M, Aiolfi R, et al.
J Thromb Haemost
. 2015 Sep;
13(11):2108-18.
PMID: 26391622
Background: Ribosomopathies constitute a class of inherited disorders characterized by defects in ribosome biogenesis and function. Classically, bone marrow (BM) failure is a clinical symptom shared between these syndromes, including...
2.
Guidotti L
J Biol Regul Homeost Agents
. 2003 Oct;
17(2):115-9.
PMID: 14518707
The aim of our research is to use animal models to elucidate the molecular basis for viral clearance and liver disease in the pathogenesis of hepatitis B virus (HBV) and...
3.
Kakimi K, Lane T, Wieland S, Asensio V, Campbell I, Chisari F, et al.
J Exp Med
. 2001 Dec;
194(12):1755-66.
PMID: 11748277
Using transgenic mice that replicate hepatitis B virus (HBV) at high levels in the liver as recipients of HBV-specific cytotoxic T lymphocytes (CTLs), we showed that the chemokines responsive to...
4.
Kakimi K, Lane T, Chisari F, Guidotti L
J Immunol
. 2001 Dec;
167(12):6701-5.
PMID: 11739482
We have previously reported that intrahepatic NK T cells activated by alpha-galactosylceramide inhibit hepatitis B virus replication noncytopathically in the liver of transgenic mice. This effect is mediated by antiviral...
5.
Heise T, Guidotti L, Chisari F
J Virol
. 2001 Jul;
75(15):6874-83.
PMID: 11435567
Hepatitis B virus (HBV) RNA is downregulated by inflammatory cytokines induced in the liver by adoptively transferred HBV-specific cytotoxic T lymphocytes (CTLs) and during murine cytomegalovirus (MCMV) infections of the...
6.
Guidotti L, Chisari F
Annu Rev Immunol
. 2001 Mar;
19:65-91.
PMID: 11244031
This review describes the contribution of noncytolytic mechanisms to the control of viral infections with a particular emphasis on the role of cytokines in these processes. It has long been...
7.
Raney A, Eggers C, KLINE E, Guidotti L, Pontoglio M, Yaniv M, et al.
J Virol
. 2001 Feb;
75(6):2900-11.
PMID: 11222715
The role of hepatocyte nuclear factor 1alpha (HNF1 alpha) in the regulation of hepatitis B virus (HBV) transcription and replication in vivo was investigated using a HNF1 alpha-null HBV transgenic...
8.
Wieland S, Guidotti L, Chisari F
J Virol
. 2001 Feb;
74(9):4165-73.
PMID: 10756029
We have previously shown that hepatitis B virus (HBV) replication is abolished in the liver of HBV transgenic mice by stimuli that induce alpha/beta interferon (IFN-alpha/beta) in the liver. The...
9.
Sette A, Oseroff C, Sidney J, Alexander J, Chesnut R, Kakimi K, et al.
J Immunol
. 2001 Jan;
166(2):1389-97.
PMID: 11145724
The sequence of the hepatitis B virus (HBV) major envelope (Env) protein (ayw subtype) was scanned for the presence of H-2(d,b) motifs. Following binding and immunogenicity testing, two new H-2(d)-restricted...
10.
Kakimi K, Guidotti L, Koezuka Y, Chisari F
J Exp Med
. 2000 Oct;
192(7):921-30.
PMID: 11015434
We have previously reported that hepatitis B virus (HBV)-specific CD8(+) cytotoxic T lymphocytes and CD4(+) helper T lymphocytes can inhibit HBV replication in the liver of HBV transgenic mice by...