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L C P G M de Groot

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Articles 36
Citations 612
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Recent Articles
1.
Kramer C, Monsegue A, Morwani-Mangnani J, Grootswagers P, Beekman M, Slagboom P, et al.
Mech Ageing Dev . 2024 Nov; 222:112002. PMID: 39490538
Background: Exercise and nutrition interventions can slow ageing-induced decline in physiology. However, effects are heterogeneous and usually studied separately per outcome domain. In the VOILA study, we simultaneously study various...
2.
Ploegmakers K, van Poelgeest E, Seppala L, van Dijk S, de Groot L, Oliai Araghi S, et al.
Pharmacol Res Perspect . 2023 Oct; 11(6):e01126. PMID: 37885367
Beta-blocker usage is inconsistently associated with increased fall risk in the literature. However, due to age-related changes and interindividual heterogeneity in pharmacokinetics and dynamics, it is difficult to predict which...
3.
Pronk A, van Poelgeest E, Seppala L, Ploegmakers K, Stricker B, Swart K, et al.
Eur Geriatr Med . 2023 Jan; 14(1):89-97. PMID: 36656485
Purpose: Antidepressants are well-established fall-risk increasing drugs (FRIDs) and therefore falls should be considered an important adverse drug event (ADE) of antidepressants. However, not all antidepressant users experience fall incidents...
4.
Huppertz V, Pilz W, Pilz Da Cunha G, de Groot L, van Helvoort A, Schols J, et al.
Front Neurol . 2022 Oct; 13:939735. PMID: 36247786
Background: Oropharyngeal dysphagia (OD) and malnutrition are associated with poor clinical outcomes after stroke. The present study evaluated (1) malnutrition risk and OD-related characteristics in patients with chronic post-stroke OD,...
5.
Pronk A, Seppala L, Trajanoska K, Stringa N, van de Loo B, de Groot L, et al.
PLoS One . 2022 Apr; 17(4):e0266590. PMID: 35421149
Background: Antidepressant use has been associated with increased fall risk. Antidepressant-related adverse drug reactions (e.g. orthostatic hypotension) depend partly on genetic variation. We hypothesized that candidate genetic polymorphisms are associated...
6.
Verwijs M, van de Rest O, van der Putten G, de Groot L, Boesveldt S
J Nutr Health Aging . 2022 Feb; 26(2):112-118. PMID: 35166301
Objectives: Dementia can lead to decreased appetite and nutritional intake. Food odor exposure has been shown to increase appetite and nutritional intake in young healthy adults. This study investigates the...
7.
Seppala L, van de Loo B, Schut M, van Schoor N, Stricker B, Kenny R, et al.
Drugs Aging . 2021 Jul; 38(9):797-805. PMID: 34224104
Introduction: Several medication classes are considered to present risk factors for falls. However, the evidence is mainly based on observational studies that often lack adequate adjustment for confounders. Therefore, we...
8.
Snijders T, Leenders M, de Groot L, van Loon L, Verdijk L
Exp Gerontol . 2019 Apr; 121:71-78. PMID: 30978433
Introduction: Although resistance type exercise training (RT) effectively increases muscle mass and strength in older individuals, it remains unclear whether gains in muscle mass and strength are maintained without continued...
9.
OKeeffe M, Kelly M, OHerlihy E, OToole P, Kearney P, Timmons S, et al.
Clin Nutr . 2019 Jan; 38(6):2477-2498. PMID: 30685297
Background & Aims: Malnutrition in older adults results in significant personal, social, and economic burden. To combat this complex, multifactorial issue, evidence-based knowledge is needed on the modifiable determinants of...
10.
Huppertz V, Halfens R, van Helvoort A, de Groot L, Baijens L, Schols J
J Nutr Health Aging . 2018 Dec; 22(10):1246-1252. PMID: 30498833
Objectives: Nursing home residents often suffer from multi-morbidities and geriatric syndromes leading to lower quality of life or mortality. Oropharyngeal dysphagia (OD) and malnutrition are profound conditions in this complex...