L B Gladden
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Explore the profile of L B Gladden including associated specialties, affiliations and a list of published articles.
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56
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1056
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Recent Articles
1.
Koirala B, Concas A, Cincotti A, Sun Y, Hernandez A, Goodwin M, et al.
Respir Physiol Neurobiol
. 2024 May;
326:104283.
PMID: 38788987
The utilization of continuous wave (CW) near-infrared spectroscopy (NIRS) device to measure non-invasively muscle oxygenation in healthy and disease states is limited by the uncertainties related to the differential path...
2.
Koirala B, Concas A, Sun Y, Gladden L, Lai N
J Appl Physiol (1985)
. 2021 Sep;
131(5):1418-1431.
PMID: 34528461
Near-infrared spectroscopy (NIRS) signals quantify the oxygenated (Δ) and deoxygenated (Δ) heme group concentrations. Δ has been preferred to Δ in evaluating skeletal muscle oxygen extraction because it is assumed...
3.
Koirala B, Saidel G, Hernandez A, Gladden L, Lai N
Adv Exp Med Biol
. 2021 May;
1269:367-372.
PMID: 33966244
Insufficient O delivery to, and uptake by skeletal muscle can produce mobility limitations for patients with chronic diseases. Near-infrared spectroscopy (NIRS) can be used to noninvasively quantify the balance between...
4.
Oldenbeuving G, McDonald J, Goodwin M, Sayilir R, Reijngoud D, Gladden L, et al.
Anaesth Intensive Care
. 2014 Jun;
42(4):507-11.
PMID: 24967767
Lactate can substitute for glucose as a metabolic substrate. We report a patient with acute liver failure who was awake despite a glucose level of 0.7 mmol/l with very high...
5.
Clanton T, Hogan M, Gladden L
Compr Physiol
. 2013 Jul;
3(3):1135-90.
PMID: 23897683
Cells must continuously monitor and couple their metabolic requirements for ATP utilization with their ability to take up O2 for mitochondrial respiration. When O2 uptake and delivery move out of...
6.
Ostergaard L, Kjaer K, Jensen K, Gladden L, Martinussen T, Pedersen P
Acta Physiol (Oxf)
. 2011 Jul;
204(3):371-81.
PMID: 21791016
Aim: To examine whether inhalation of CO(2) -enriched gas would increase steady-state VO(2) during exercise and enlarge O(2) deficit. Methods: Ten physically active men (VO(2) 53.7 ± 3.6 mL min(-1)...
7.
McAnulty S, McAnulty L, Pascoe D, Gropper S, Keith R, Morrow J, et al.
Int J Sports Med
. 2005 Mar;
26(3):188-92.
PMID: 15776334
The purpose of this investigation was to examine oxidative markers after exercise in a hyperthermic environment (35 degrees C, 70 % RH) (Hot) versus a neutral environment (25 degrees C,...
8.
Sahlin K, Sorensen J, Gladden L, Rossiter H, Pedersen P
J Physiol
. 2005 Mar;
564(Pt 3):765-73.
PMID: 15746165
We investigated the hypothesis that the pulmonary oxygen uptake (VO2) slow component is related to a progressive increase in muscle lactate concentration and that prior heavy exercise (PHE) with pronounced...
9.
Gladden L
J Physiol
. 2004 May;
558(Pt 1):5-30.
PMID: 15131240
For much of the 20th century, lactate was largely considered a dead-end waste product of glycolysis due to hypoxia, the primary cause of the O2 debt following exercise, a major...
10.
Hogan M, Grassi B, Samaja M, Stary C, Gladden L
J Appl Physiol (1985)
. 2003 Jun;
95(3):1139-44.
PMID: 12794032
The purpose of this study was to test the hypothesis that increasing muscle contraction frequency, which alters the duty cycle and metabolic rate, would increase the contribution of the contractile...