L A Stargell
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Explore the profile of L A Stargell including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
391
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Recent Articles
1.
ROBINSON M, Yatherajam G, Ranallo R, Bric A, Paule M, Stargell L
Mol Cell Biol
. 2005 Jan;
25(3):945-57.
PMID: 15657423
TFIIA interacts with TFIID via association with TATA binding protein (TBP) and TBP-associated factor 11 (TAF11). We previously identified a mutation in the small subunit of TFIIA (toa2-I27K) that is...
2.
Stewart J, Stargell L
J Biol Chem
. 2001 Jun;
276(32):30078-84.
PMID: 11402056
To determine the mechanistic differences between canonical and noncanonical TATA elements, we compared the functional activity of two sequences: TATAAA (canonical) and CATAAA (noncanonical). The TATAAA element can support high...
3.
Stargell L, Ogg R, Adkins J, ROBINSON M, Lumb K
Proteins
. 2001 Mar;
43(2):227-32.
PMID: 11276091
TFIIA contributes to transcription initiation by stabilizing the TBP-TATA interaction and by mediating the response to transcriptional activators and inhibitors. TFIIA contains a six-stranded beta-sheet domain and a four-helix bundle....
4.
Kraemer S, Ranallo R, Ogg R, Stargell L
Mol Cell Biol
. 2001 Mar;
21(5):1737-46.
PMID: 11238911
TFIIA and TATA-binding protein (TBP) associate directly at the TATA element of genes transcribed by RNA polymerase II. In vivo, TBP is complexed with approximately 14 TBP-associated factors (TAFs) to...
5.
Stargell L, Moqtaderi Z, Dorris D, Ogg R, Struhl K
J Biol Chem
. 2000 Apr;
275(17):12374-80.
PMID: 10777519
The physiological role of TFIIA was investigated by analyzing transcription in a yeast strain that contains a TATA-binding protein (TBP) mutant (N2-1) defective for interacting with TFIIA. In cells containing...
6.
Campbell K, Ranallo R, Stargell L, Lumb K
Biochemistry
. 2000 Mar;
39(10):2633-8.
PMID: 10704213
The TATA-binding protein (TBP) plays an important role in transcriptional initiation by all three nuclear RNA polymerases. TBP contains a conserved C-terminal domain (cTBP) that binds DNA. Crystallographic studies of...
7.
Powell P, DeMartini J, Azari P, Stargell L, Cordain L, Tucker A
J Theor Biol
. 2000 Feb;
202(3):213-29.
PMID: 10660476
The genetic makeup of animal and plant populations is determined by established principles and concepts. Ecology and evolution provide a basic theoretical framework for understanding how genetic changes occur in...
8.
Ranallo R, Struhl K, Stargell L
Mol Cell Biol
. 1999 May;
19(6):3951-7.
PMID: 10330135
Using an intragenic complementation screen, we have identified a temperature-sensitive TATA-binding protein (TBP) mutant (K151L, K156Y) that is defective for interaction with certain yeast TBP-associated factors (TAFs) at the restrictive...
9.
Yan J, Garrus J, Giebler H, Stargell L, Nyborg J
J Mol Biol
. 1998 Aug;
281(3):395-400.
PMID: 9698555
The oncoprotein Tax, encoded by the human T-cell leukemia virus type I (HTLV-I), is required for high-level viral transcription and is strongly linked to HTLV-I-associated malignant transformation. Recent evidence suggests...
10.
Stargell L, Struhl K
Trends Genet
. 1996 Aug;
12(8):311-5.
PMID: 8783941
Transcriptional activation involves the regulated assembly of multiprotein complexes on promoter DNA in the context of the repressive effects of chromatin. How do activators orchestrate this complicated phenomenon in vivo?...