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L A Kirshenbaum

Explore the profile of L A Kirshenbaum including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 903
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Kirshenbaum L, Schneider M
Trends Cardiovasc Med . 2011 Jan; 5(6):230-5. PMID: 21232265
Identification of cell cycle regulators-tumor suppressor "pocket" proteins, cyclins, cyclin-dependent protein kinases (cdks), and an emerging family of cdk inhibitors-has fueled fundamental research into mechanisms that regulate cell proliferation, as...
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Dorn 2nd G, Kirshenbaum L
Oncogene . 2009 Jul; 27 Suppl 1:S158-67. PMID: 19641501
Programmed cardiac myocyte death contributes to pathological ventricular remodeling and the progression of myocardial infarction or pressure overload hypertrophy to dilated cardiomyopathy. Recent work has identified importance of stress-mediated transcriptional...
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Hamacher-Brady A, Brady N, Logue S, Sayen M, Jinno M, Kirshenbaum L, et al.
Cell Death Differ . 2006 Apr; 14(1):146-57. PMID: 16645637
Ischemia and reperfusion (I/R) injury is associated with extensive loss of cardiac myocytes. Bnip3 is a mitochondrial pro-apoptotic Bcl-2 protein which is expressed in the adult myocardium. To investigate if...
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Regula K, Kirshenbaum L
Apoptosis . 2003 Nov; 4(4):229-34. PMID: 14634272
Apoptosis or programmed cell death is an important physiologic event crucial for the selective removal of damaged or unwanted cells from body tissues. In the cardiovascular system, apoptosis has been...
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Cahill S, Kirshenbaum L, Gross G
J Cardiovasc Pharmacol . 2001 Aug; 38(3):460-7. PMID: 11486250
The antiarrhythmic agent propafenone and its primary electropharmacologically active metabolite, 5-hydroxypropafenone, are known inhibitors of cardiac myocyte repolarizing currents. We recently documented potent propafenone inhibition of the transient outward potassium...
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Regula K, Kirshenbaum L
J Mol Cell Cardiol . 2001 Jul; 33(8):1435-45. PMID: 11448132
The tumor suppressor p53 is known to regulate gene transcription and apoptosis in mammalian cells. In the present study we ascertain whether these events are mutually dependent and obligatorily linked...
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Elmadhoun B, Wang G, Kirshenbaum L, Burczynski F
Eur J Biochem . 2001 Jun; 268(11):3145-53. PMID: 11389715
The role of extracellular binding proteins in the rate of [3H]palmitate uptake by neonatal cardiac myocytes and hepatocytes was investigated using a model-independent approach. Binding proteins used in this study...
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Kirshenbaum L
Circ Res . 2001 May; 88(10):978-80. PMID: 11375264
No abstract available.
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GUREVICH R, Regula K, Kirshenbaum L
Circulation . 2001 Apr; 103(15):1984-91. PMID: 11306528
Background: In this study, we ascertain whether caspase 8 activation and mitochondrial defects underlie apoptosis of ventricular myocytes during hypoxia. As an approach to circumvent the potential shortcomings surrounding the...