L A Alger
Overview
Explore the profile of L A Alger including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
2
Citations
103
Followers
0
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Recent Articles
1.
Hoshikawa Y, Voelkel N, Gesell T, Moore M, Morris K, Alger L, et al.
Am J Respir Crit Care Med
. 2001 Jul;
164(2):314-8.
PMID: 11463607
Prostacyclin (PGI(2)) reduces pulmonary vascular resistance and attenuates vascular smooth muscle cell proliferation through signal transduction following ligand binding to its receptor. Because patients with severe pulmonary hypertension have a...
2.
Geraci M, Gao B, SHEPHERD D, Moore M, Westcott J, Fagan K, et al.
J Clin Invest
. 1999 Jun;
103(11):1509-15.
PMID: 10359560
Prostacyclin synthase (PGIS) is the final committed enzyme in the metabolic pathway leading to prostacyclin (PGI2) production. Patients with severe pulmonary hypertension have a PGIS deficiency of their precapillary vessels,...