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L-Q Gu

Explore the profile of L-Q Gu including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 82
Followers 0
Related Specialties
Biochemistry
Oncology
Toxicology
Top 10 Co-Authors
Z-S Huang
M Huang
Z Zuo
X-F Zhu
R Deng
J-M Zhou
Y Pan
L-Z Zhao
Z-Y Huang
Y-X Zeng
Published In
Xenobiotica
Transplant Proc
Leukemia
Oncogene
Eur J Med Chem
Affiliations
Soon will be listed here.
Recent Articles
1.
Pharmacokinetic characterization of hydroxylpropyl-beta-cyclodextrin-included complex of cryptotanshinone, an investigational cardiovascular drug purified from Danshen (Salvia miltiorrhiza)
Pan Y, Bi H, Zhong G, Chen X, Zuo Z, Zhao L, et al.
Xenobiotica . 2008 Mar; 38(4):382-98. PMID: 18340563
1. The study aimed to investigate the pharmacokinetics of cryptotanshinone in a hydroxylpropyl-beta-cyclodextrin-included complex in dogs and rats. 2. Animals were administrated the inclusion complex of cryptotanshinone and the concentrations...
2.
Preclinical factors affecting the pharmacokinetic behaviour of tanshinone IIA, an investigational new drug isolated from Salvia miltiorrhiza for the treatment of ischaemic heart diseases
Bi H, Zuo Z, Chen X, Xu C, Wen Y, Sun H, et al.
Xenobiotica . 2008 Jan; 38(2):185-222. PMID: 18197559
Tanshinone IIA (TSIIA) is a major active triterpenoid isolated from Salvia miltiorrhiza. The purposes of this study were to investigate various preclinical factors that determined the pharmacokinetics of TSIIA. After...
3.
Inhibition of myc promoter and telomerase activity and induction of delayed apoptosis by SYUIQ-5, a novel G-quadruplex interactive agent in leukemia cells
Liu J, Deng R, Guo J, Zhou J, Feng G, Huang Z, et al.
Leukemia . 2007 Mar; 21(6):1300-2. PMID: 17392822
No abstract available.
4.
Synthesis, DNA binding and cytotoxicity of new pyrazole emodin derivatives
Tan J, Zhang Q, Huang Z, Chen Y, Wang X, Gu L, et al.
Eur J Med Chem . 2006 May; 41(9):1041-7. PMID: 16716458
A series of new anthrapyrazoles were derived from emodin by attaching various cationic alkyl amino side chains onto a pyrazole ring which had been incorporated into the anthraquinone chromophore. Compared...
5.
Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines
Zhou J, Zhu X, Lu Y, Deng R, Huang Z, Mei Y, et al.
Oncogene . 2005 Sep; 25(4):503-11. PMID: 16170347
Agents stabilizing G-quadruplexes have the potential to interfere with telomere replication by blocking the elongation step catalysed by telomerase or telomerase-independent mechanism and could therefore act as antitumor agents. In...
6.
Early monitoring of lymphocyte subsets in patients with hand allotransplantation
Zheng X, Pei G, Qiu Y, Zhu L, Gu L
Transplant Proc . 2002 Dec; 34(8):3401-4. PMID: 12493482
No abstract available.