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Kyung-Won Min

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Articles 33
Citations 484
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Recent Articles
1.
Yeom E, Mun H, Lim J, Chun Y, Min K, Lambert J, et al.
Aging Cell . 2025 Mar; :e70022. PMID: 40070010
The metazoan lifespan is determined in part by a complex signaling network that regulates energy metabolism and stress responses. Key signaling hubs in this network include insulin/IGF-1, AMPK, mTOR, and...
2.
Gupta H, Lee J, Hoffman K, Min K, Yoon J
Methods Mol Biol . 2024 Nov; 2863:139-149. PMID: 39535709
Eukaryotic RNA synthesis and degradation are intricately regulated, impacting on gene expression dynamics. RNA stability varies in individual transcripts and is modulated by trans-acting factors such as microRNAs, long noncoding...
3.
Chung H, Nguyen T, Lee J, Huh Y, Ko S, Lim H, et al.
Neurotherapeutics . 2024 Oct; 21(6):e00458. PMID: 39384453
Peripheral neuropathies (PNs) are common diseases in elderly individuals characterized by Schwann cell (SC) dysfunction and irreversible Wallerian degeneration (WD). Although the molecular mechanisms of PN onset and progression have...
4.
Min K, Choi K, Mun H, Ko S, Lee J, Sagum C, et al.
J Cell Sci . 2024 Sep; 137(21). PMID: 39308343
Argonaute (AGO), a component of RNA-induced silencing complexes (RISCs), is a representative RNA-binding protein (RBP) known to bind with mature microRNAs (miRNAs) and is directly involved in post-transcriptional gene silencing....
5.
Min K, Jo M, Song M, Lee J, Shim M, Kim K, et al.
RNA Biol . 2024 Feb; 21(1):1-15. PMID: 38372062
Although Argonaute (AGO) proteins have been the focus of microRNA (miRNA) studies, we observed AGO-free mature miRNAs directly interacting with RNA-binding proteins, implying the sophisticated nature of fine-tuning gene regulation...
6.
Lee J, Mun H, Kim J, Ko S, Kim Y, Shim M, et al.
Biology (Basel) . 2023 Dec; 12(12). PMID: 38132359
Although ionizing radiation (IR) is widely used for therapeutic and research purposes, studies on low-dose ionizing radiation (LDIR) are limited compared with those on other IR approaches, such as high-dose...
7.
Lee T, Han H, Polash A, Cho S, Lee J, Ra E, et al.
Nat Commun . 2022 Sep; 13(1):5203. PMID: 36057640
Inflammatory cytokines are key signaling molecules that can promote an immune response, thus their RNA turnover must be tightly controlled during infection. Most studies investigate the RNA decay pathways in...
8.
Gulati R, Johnston M, Rivas M, Cast A, Kumbaji M, Hanlon M, et al.
Hepatol Commun . 2022 Aug; 6(10):2950-2963. PMID: 36000549
Fibrolamellar hepatocellular carcinoma (FLC) is a disease that occurs in children and young adults. The development of FLC is associated with creation of a fusion oncoprotein DNAJB1-PKAc kinase, which activates...
9.
Whyte S, Karns R, Min K, Cho J, Lee S, Lake C, et al.
Cancer Rep (Hoboken) . 2022 Jul; 6(1):e1685. PMID: 35859536
Background: Pediatric hepatocellular carcinoma (HCC) is a group of liver cancers whose mechanisms behind their pathogenesis and progression are poorly understood. Aim: We aimed to identify alterations in the expression...
10.
Park M, Zhang L, Min K, Cho J, Yeh C, Moon H, et al.
Cell Metab . 2021 Dec; 33(12):2380-2397.e9. PMID: 34879239
Accelerated glycolysis is the main metabolic change observed in cancer, but the underlying molecular mechanisms and their role in cancer progression remain poorly understood. Here, we show that the deletion...