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Richard W Zealy

Explore the profile of Richard W Zealy including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 228
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Recent Articles
1.
Sun Q, Tripathi V, Yoon J, Singh D, Hao Q, Min K, et al.
Nucleic Acids Res . 2018 Aug; 46(19):10405-10416. PMID: 30102375
Long non-coding RNAs (lncRNAs) regulate vital biological processes, including cell proliferation, differentiation and development. A subclass of lncRNAs is synthesized from microRNA (miRNA) host genes (MIRHGs) due to pre-miRNA processing,...
2.
Min K, Zealy R, Davila S, Fomin M, Cummings J, Makowsky D, et al.
Aging Cell . 2018 Mar; 17(3):e12753. PMID: 29573145
Gene expression is dynamically regulated in a variety of mammalian physiologies. During mammalian aging, there are changes that occur in protein expression that are highly controlled by the regulatory steps...
3.
Zealy R, Fomin M, Davila S, Makowsky D, Thigpen H, Mcdowell C, et al.
Biochim Biophys Acta Gene Regul Mech . 2018 Feb; 1861(3):224-234. PMID: 29421307
Eukaryotic mRNA metabolism regulates its stability, localization, and translation using complementarity with counter-part RNAs. To modulate their stability, small and long noncoding RNAs can establish complementarity with their target mRNAs....
4.
Min K, Davila S, Zealy R, Lloyd L, Lee I, Lee R, et al.
Biochim Biophys Acta Gene Regul Mech . 2017 May; 1860(7):761-772. PMID: 28487214
Post-transcriptional gene regulation is an important step in eukaryotic gene expression. The last step to govern production of nascent peptides is during the process of mRNA translation. mRNA translation is...
5.
Min K, Jo M, Shin S, Davila S, Zealy R, Kang S, et al.
Nucleic Acids Res . 2017 Mar; 45(10):6064-6073. PMID: 28334781
Eukaryotic mRNA decay is tightly modulated by RNA-binding proteins (RBPs) and microRNAs (miRNAs). RBP AU-binding factor 1 (AUF1) has four isoforms resulting from alternative splicing and is critical for miRNA-mediated...
6.
Zealy R, Wrenn S, Davila S, Min K, Yoon J
Wiley Interdiscip Rev RNA . 2017 Jan; 8(5). PMID: 28130820
microRNA (miRNA) and RNA-binding proteins (RBPs) have been studied widely in post-transcriptional gene regulation. Previous work has focused on defining how miRNA and RBPs modulate target mRNA decay and translation...