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Kyung-Hyun Park-Min

Explore the profile of Kyung-Hyun Park-Min including associated specialties, affiliations and a list of published articles. Areas
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Articles 55
Citations 2103
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Recent Articles
1.
Heilbronner A, Blumberg O, Krez A, McMahon D, Mintz D, Lane J, et al.
Leuk Lymphoma . 2025 Jan; 1-4. PMID: 39813635
No abstract available.
2.
Kaneko K, Tsai J, Menez D, Oh B, Suh A, Bae S, et al.
JCI Insight . 2024 Nov; 9(22). PMID: 39576015
Osteoclasts are the sole bone-resorbing cells and are formed by the fusion of osteoclast precursor cells (OCPs) derived from myeloid lineage cells. Animal studies reveal that circulating OCPs (cOCPs) in...
3.
Kim H, Choi I, Umemoto A, Bae S, Kaneko K, Mizuno M, et al.
Bone Res . 2024 Aug; 12(1):48. PMID: 39191742
Osteoclasts are multinucleated bone-resorbing cells, and their formation is tightly regulated to prevent excessive bone loss. However, the mechanisms by which osteoclast formation is restricted remain incompletely determined. Here, we...
4.
Park-Min K, Mun S, Bockman R, McDonald M
J Clin Endocrinol Metab . 2023 Dec; 109(5):e1373-e1378. PMID: 38060842
Osteomorphs are a newly described osteoclast lineage cell in mice, which are suggested to play a significant role in the maintenance of bone resorption. Preclinical investigations revealed that osteomorphs are...
5.
Tsai J, Kaneko K, Suh A, Bockman R, Park-Min K
J Bone Metab . 2023 Jul; 30(2):127-140. PMID: 37449346
Osteoclasts are multinucleated bone-resorbing cells and a key player in bone remodeling for health and disease. Since the discovery of osteoclasts in 1873, the structure and function of osteoclasts and...
6.
Bae S, Kim K, Kang K, Kim H, Lee M, Oh B, et al.
Cell Mol Immunol . 2022 Dec; 20(1):94-109. PMID: 36513810
Monocyte/macrophage lineage cells are highly plastic and can differentiate into various cells under different environmental stimuli. Bone-resorbing osteoclasts are derived from the monocyte/macrophage lineage in response to receptor activator of...
7.
Murata K, Fang C, Terao C, Giannopoulou E, Lee Y, Lee M, et al.
Immunity . 2022 Nov; 55(11):2209. PMID: 36351378
No abstract available.
8.
Park-Min K, Lorenzo J
Bone . 2022 Oct; 165:116576. PMID: 36195243
Osteoclasts are the only cells that can efficiently resorb bone. They do so by sealing themselves on to bone and removing the mineral and organic components. Osteoclasts are essential for...
9.
Oh W, Yang Y, Xie J, Ma H, Kim J, Park K, et al.
Mol Ther . 2022 Oct; 31(2):435-453. PMID: 36184851
Treating osteoporosis and associated bone fractures remains challenging for drug development in part due to potential off-target side effects and the requirement for long-term treatment. Here, we identify recombinant adeno-associated...
10.
Bae S, Oh B, Tsai J, Park P, Greenblatt M, Giannopoulou E, et al.
Front Cell Dev Biol . 2022 Sep; 10:920683. PMID: 36060812
Osteoclasts are bone-resorbing cells that undergo extensive changes in morphology throughout their differentiation. Altered osteoclast differentiation and activity lead to changes in pathological bone resorption. The mammalian target of rapamycin...