Eugenia Giannopoulou
Overview
Explore the profile of Eugenia Giannopoulou including associated specialties, affiliations and a list of published articles.
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18
Citations
1876
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Recent Articles
1.
Rivera-Correa J, Gupta S, Ricker E, Flores-Castro D, Jenkins D, Vulcano S, et al.
JCI Insight
. 2025 Feb;
10(5).
PMID: 39903532
The mechanisms utilized by differentiating B cells to withstand highly damaging conditions generated during severe infections, like the massive hemolysis that accompanies malaria, are poorly understood. Here, we demonstrate that...
2.
Kaneko K, Tsai J, Menez D, Oh B, Suh A, Bae S, et al.
JCI Insight
. 2024 Nov;
9(22).
PMID: 39576015
Osteoclasts are the sole bone-resorbing cells and are formed by the fusion of osteoclast precursor cells (OCPs) derived from myeloid lineage cells. Animal studies reveal that circulating OCPs (cOCPs) in...
3.
Kim H, Choi I, Umemoto A, Bae S, Kaneko K, Mizuno M, et al.
Bone Res
. 2024 Aug;
12(1):48.
PMID: 39191742
Osteoclasts are multinucleated bone-resorbing cells, and their formation is tightly regulated to prevent excessive bone loss. However, the mechanisms by which osteoclast formation is restricted remain incompletely determined. Here, we...
4.
Li S, Miller C, Giannopoulou E, Hu X, Ivashkiv L, Zhao B
J Clin Invest
. 2022 May;
132(10).
PMID: 35575092
No abstract available.
5.
Chen Z, Castro D, Gupta S, Phalke S, Manni M, Rivera-Correa J, et al.
Arthritis Rheumatol
. 2022 Apr;
74(9):1544-1555.
PMID: 35438841
Objective: Age-associated/autoimmune B cells (ABCs) are an emerging B cell subset with aberrant expansion in systemic lupus erythematosus. ABC generation and differentiation exhibit marked sexual dimorphism, and Toll-like receptor 7...
6.
Bae S, Park P, Lee Y, Mun S, Giannopoulou E, Fujii T, et al.
Cell Rep
. 2021 Jun;
35(11):109264.
PMID: 34133930
MYC activates different metabolic programs in a cell-type- and cell-status-dependent manner. However, the role of MYC in inflammatory macrophages has not yet been determined. Metabolic and molecular analyses reveal that...
7.
Kusnadi A, Park S, Yuan R, Pannellini T, Giannopoulou E, Oliver D, et al.
Immunity
. 2019 Jul;
51(2):241-257.e9.
PMID: 31303399
Cytokine tumor necrosis factor (TNF)-mediated macrophage polarization is important for inflammatory disease pathogenesis, but the mechanisms regulating polarization are not clear. We performed transcriptomic and epigenomic analysis of the TNF...
8.
Donlin L, Park S, Giannopoulou E, Ivovic A, Park-Min K, Siegel R, et al.
Nat Rev Rheumatol
. 2019 Apr;
15(6):327-339.
PMID: 31000790
Rheumatic diseases have complex aetiologies that are not fully understood, which makes the study of pathogenic mechanisms in these diseases a challenge for researchers. Next-generation sequencing (NGS) and related omics...
9.
Inoue K, Deng Z, Chen Y, Giannopoulou E, Xu R, Gong S, et al.
Nat Commun
. 2018 Oct;
9(1):4108.
PMID: 30291236
Targeting microRNAs recently shows significant therapeutic promise; however, such progress is underdeveloped in treatment of skeletal diseases with osteolysis, such as osteoporosis and rheumatoid arthritis (RA). Here, we identified miR-182...
10.
Park S, Kang K, Giannopoulou E, Qiao Y, Kang K, Kim G, et al.
Nat Immunol
. 2017 Aug;
18(10):1104-1116.
PMID: 28825701
Cross-regulation of Toll-like receptor (TLR) responses by cytokines is essential for effective host defense, avoidance of toxicity and homeostasis, but the underlying mechanisms are not well understood. Our comprehensive epigenomics...