Kyu-Tae Kim
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Explore the profile of Kyu-Tae Kim including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
2482
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Recent Articles
1.
Kwon M, Kim G, Kim R, Kim K, Kim S, Smith S, et al.
J Immunother Cancer
. 2022 Jul;
10(7).
PMID: 35790315
Background: Targeting the DNA damage repair (DDR) pathways is an attractive strategy for boosting cancer immunotherapy. Ceralasertib (AZD6738) is an oral kinase inhibitor of ataxia telangiectasia and Rad3 related protein,...
2.
Jung J, Kim K, Chung N, Baek U, Nahm S
Polymers (Basel)
. 2022 Apr;
14(7).
PMID: 35406341
We developed a method for characterizing permeation parameters in hydrogen sorption and desorption processes in polymers using the volumetric measurement technique. The technique was utilized for three polymers: nitrile butadiene...
3.
Kwon M, An M, Klempner S, Lee H, Kim K, Sa J, et al.
Cancer Discov
. 2021 Apr;
11(9):2168-2185.
PMID: 33846173
Sequence alterations in microsatellites and an elevated mutational burden are observed in 20% of gastric cancers and associated with clinical response to anti-PD-1 antibodies. However, 50% of microsatellite instability-high (MSI-H)...
4.
Volk A, Mebrahtu A, Ko B, Lundqvist M, Karlander M, Lee H, et al.
Drugs R D
. 2021 Mar;
21(2):157-168.
PMID: 33721246
Background: Monoclonal antibodies (mAbs) have proved to be a valuable tool for the treatment of different cancer types. However, clinical use of an increasing number of mAbs, have also highlighted...
5.
Izzo F, Lee S, Poran A, Chaligne R, Gaiti F, Gross B, et al.
Nat Genet
. 2020 Mar;
52(4):378-387.
PMID: 32203468
Mutations in genes involved in DNA methylation (DNAme; for example, TET2 and DNMT3A) are frequently observed in hematological malignancies and clonal hematopoiesis. Applying single-cell sequencing to murine hematopoietic stem and...
6.
Lhoumaud P, Sethia G, Izzo F, Sakellaropoulos T, Snetkova V, Vidal S, et al.
Genome Biol
. 2019 Nov;
20(1):248.
PMID: 31752933
Activation of regulatory elements is thought to be inversely correlated with DNA methylation levels. However, it is difficult to determine whether DNA methylation is compatible with chromatin accessibility or transcription...
7.
Jung J, Jeon S, Kim K, Lee C, Baek U, Chung K
Sci Rep
. 2019 Sep;
9(1):13035.
PMID: 31506543
Nondestructive impedance spectroscopy (IS) was developed and demonstrated to detect the effects of hydrogen on nitrile butadiene rubber exposed to hydrogen gas (H) at high pressures up to 10 MPa....
8.
Nam A, Kim K, Chaligne R, Izzo F, Ang C, Taylor J, et al.
Nature
. 2019 Jul;
571(7765):355-360.
PMID: 31270458
Defining the transcriptomic identity of malignant cells is challenging in the absence of surface markers that distinguish cancer clones from one another, or from admixed non-neoplastic cells. To address this...
9.
Gaiti F, Chaligne R, Gu H, Brand R, Kothen-Hill S, Schulman R, et al.
Nature
. 2019 May;
569(7757):576-580.
PMID: 31092926
Genetic and epigenetic intra-tumoral heterogeneity cooperate to shape the evolutionary course of cancer. Chronic lymphocytic leukaemia (CLL) is a highly informative model for cancer evolution as it undergoes substantial genetic...
10.
Pastore A, Gaiti F, Lu S, Brand R, Kulm S, Chaligne R, et al.
Nat Commun
. 2019 Apr;
10(1):1874.
PMID: 31015400
Cancer evolution is fueled by epigenetic as well as genetic diversity. In chronic lymphocytic leukemia (CLL), intra-tumoral DNA methylation (DNAme) heterogeneity empowers evolution. Here, to comprehensively study the epigenetic dimension...