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Kyobi Skutt-Kakaria

Explore the profile of Kyobi Skutt-Kakaria including associated specialties, affiliations and a list of published articles. Areas
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Citations 397
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Recent Articles
1.
Lesser E, Azevedo A, Phelps J, Elabbady L, Cook A, Syed D, et al.
Nature . 2024 Jun; 631(8020):369-377. PMID: 38926579
Animal movement is controlled by motor neurons (MNs), which project out of the central nervous system to activate muscles. MN activity is coordinated by complex premotor networks that facilitate the...
2.
Azevedo A, Lesser E, Phelps J, Mark B, Elabbady L, Kuroda S, et al.
Nature . 2024 Jun; 631(8020):360-368. PMID: 38926570
A deep understanding of how the brain controls behaviour requires mapping neural circuits down to the muscles that they control. Here, we apply automated tools to segment neurons and identify...
3.
Lesser E, Azevedo A, Phelps J, Elabbady L, Cook A, Syed D, et al.
bioRxiv . 2023 Jul; PMID: 37398440
Animal movement is controlled by motor neurons (MNs), which project out of the central nervous system to activate muscles. MN activity is coordinated by complex premotor networks that allow individual...
4.
de Bivort B, Buchanan S, Skutt-Kakaria K, Gajda E, Ayroles J, OLeary C, et al.
Front Behav Neurosci . 2022 Jun; 16:836626. PMID: 35692381
Individual animals behave differently from each other. This variability is a component of personality and arises even when genetics and environment are held constant. Discovering the biological mechanisms underlying behavioral...
5.
Werkhoven Z, Bravin A, Skutt-Kakaria K, Reimers P, Pallares L, Ayroles J, et al.
Elife . 2021 Oct; 10. PMID: 34664550
Individual animals vary in their behaviors. This is true even when they share the same genotype and were reared in the same environment. Clusters of covarying behaviors constitute behavioral syndromes,...
6.
Ayroles J, Buchanan S, OLeary C, Skutt-Kakaria K, Grenier J, Clark A, et al.
Proc Natl Acad Sci U S A . 2015 May; 112(21):6706-11. PMID: 25953335
Quantitative genetics has primarily focused on describing genetic effects on trait means and largely ignored the effect of alternative alleles on trait variability, potentially missing an important axis of genetic...
7.
Hubert C, Bradley R, Ding Y, Toledo C, Herman J, Skutt-Kakaria K, et al.
Genes Dev . 2013 May; 27(9):1032-45. PMID: 23651857
To identify key regulators of human brain tumor maintenance and initiation, we performed multiple genome-wide RNAi screens in patient-derived glioblastoma multiforme (GBM) stem cells (GSCs). These screens identified the plant...
8.
Ding Y, Hubert C, Herman J, Corrin P, Toledo C, Skutt-Kakaria K, et al.
Cancer Discov . 2012 Nov; 3(2):198-211. PMID: 23154965
Unlabelled: To identify new candidate therapeutic targets for glioblastoma multiforme, we combined functional genetics and glioblastoma network modeling to identify kinases required for the growth of patient-derived brain tumor-initiating cells...
9.
Chen X, Skutt-Kakaria K, Davison J, Ou Y, Choi E, Malik P, et al.
Genes Dev . 2012 Oct; 26(22):2499-511. PMID: 23105005
G9a and GLP are conserved protein methyltransferases that play key roles during mammalian development through mono- and dimethylation of histone H3 Lys 9 (H3K9me1/2), modifications associated with transcriptional repression. During...
10.
Kutter E, Skutt-Kakaria K, Blasdel B, El-Shibiny A, Castano A, Bryan D, et al.
Virol J . 2011 Sep; 8:430. PMID: 21899740
Phage vB_EcoM_CBA120 (CBA120), isolated against Escherichia coli O157:H7 from a cattle feedlot, is morphologically very similar to the classic phage ViI of Salmonella enterica serovar Typhi. Until recently, little was...