Kyle Tsui
Overview
Explore the profile of Kyle Tsui including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
888
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Recent Articles
1.
Liachko I, Youngblood R, Tsui K, Bubb K, Queitsch C, Raghuraman M, et al.
PLoS Genet
. 2014 Mar;
10(3):e1004169.
PMID: 24603708
The well-studied DNA replication origins of the model budding and fission yeasts are A/T-rich elements. However, unlike their yeast counterparts, both plant and metazoan origins are G/C-rich and are associated...
2.
de Boer C, van Bakel H, Tsui K, Li J, Morris Q, Nislow C, et al.
Genome Res
. 2013 Oct;
24(1):154-66.
PMID: 24170600
Identifying genes in the genomic context is central to a cell's ability to interpret the genome. Yet, in general, the signals used to define eukaryotic genes are poorly described. Here,...
3.
van Bakel H, Tsui K, Gebbia M, Mnaimneh S, Hughes T, Nislow C
PLoS Genet
. 2013 May;
9(5):e1003479.
PMID: 23658529
Nucleosomes in all eukaryotes examined to date adopt a characteristic architecture within genes and play fundamental roles in regulating transcription, yet the identity and precise roles of many of the...
4.
Srikumar T, Lewicki M, Costanzo M, Tkach J, van Bakel H, Tsui K, et al.
J Cell Biol
. 2013 Apr;
201(1):145-63.
PMID: 23547032
Like ubiquitin, the small ubiquitin-related modifier (SUMO) proteins can form oligomeric "chains," but the biological functions of these superstructures are not well understood. Here, we created mutant yeast strains unable...
5.
Ammar R, Torti D, Tsui K, Gebbia M, Durbic T, Bader G, et al.
Elife
. 2012 Dec;
1:e00078.
PMID: 23240084
The eukaryotic nucleosome is the fundamental unit of chromatin, comprising a protein octamer that wraps ∼147 bp of DNA and has essential roles in DNA compaction, replication and gene expression....
6.
Xu M, Soloveychik M, Ranger M, Schertzberg M, Shah Z, Raisner R, et al.
Dev Cell
. 2012 Nov;
23(5):1059-71.
PMID: 23123093
Gametes are among the most highly specialized cells produced during development. Although gametogenesis culminates in transcriptional quiescence in plants and animals, regulatory mechanisms controlling this are unknown. Here, we confirm...
7.
Ryan O, Shapiro R, Kurat C, Mayhew D, Baryshnikova A, Chin B, et al.
Science
. 2012 Sep;
337(6100):1353-6.
PMID: 22984072
The dimorphic switch from a single-cell budding yeast to a filamentous form enables Saccharomyces cerevisiae to forage for nutrients and the opportunistic pathogen Candida albicans to invade human tissues and...
8.
Tsui K, Durbic T, Gebbia M, Nislow C
Methods Mol Biol
. 2011 Dec;
833:389-411.
PMID: 22183606
The basic unit of chromatin is double-stranded DNA wrapped around nucleosome core particles, the -classic "beads-on-a-string" described by Kornberg and colleagues. The history of chromatin studies has experienced many peaks,...
9.
Kurat C, Lambert J, van Dyk D, Tsui K, van Bakel H, Kaluarachchi S, et al.
Genes Dev
. 2011 Dec;
25(23):2489-501.
PMID: 22156209
The cell cycle-regulated expression of core histone genes is required for DNA replication and proper cell cycle progression in eukaryotic cells. Although some factors involved in histone gene transcription are...
10.
Guan Y, Yao V, Tsui K, Gebbia M, Dunham M, Nislow C, et al.
BMC Genomics
. 2011 Sep;
12:466.
PMID: 21942931
Background: Genome-wide nucleosome occupancy is negatively related to the average level of transcription factor motif binding based on studies in yeast and several other model organisms. The degree to which...