Kyle A Emmitte
Overview
Explore the profile of Kyle A Emmitte including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
63
Citations
1163
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Rangan R, Petty R, Acharya S, Emmitte K, do Valle R, Lam C, et al.
bioRxiv
. 2025 Mar;
PMID: 40027829
Psychedelics are well known for their ability to produce profoundly altered states of consciousness. But, more importantly, the effects of psychedelics can influence neurobehavioral changes that last well after these...
2.
Mishra N, Spitznagel B, Du Y, Mohamed Y, Qin Y, Weaver C, et al.
Molecules
. 2024 Dec;
29(23).
PMID: 39683653
Epilepsy of infancy with migrating focal seizures (EIMFS) is a rare, serious, and pharmacoresistant epileptic disorder often linked to gain-of-function mutations in the gene. encodes the sodium-activated potassium channel known...
3.
Qunies A, Spitznagel B, Du Y, Peprah P, Mohamed Y, Weaver C, et al.
Molecules
. 2024 Jun;
29(11).
PMID: 38893312
Gain-of-function mutations in the gene, which encodes the sodium-activated potassium channel known as SLACK, are associated with the rare but devastating developmental and epileptic encephalopathy known as epilepsy of infancy...
4.
McKay T, Emmitte K, German C, Karamichos D
Bioengineering (Basel)
. 2023 Oct;
10(10).
PMID: 37892857
Quercetin is a polyphenol of the flavonoid class of secondary metabolites that is widely distributed in the plant kingdom. Quercetin has been found to exhibit potent bioactivity in the areas...
5.
Shore A, Li K, Safari M, Qunies A, Spitznagel B, Weaver C, et al.
bioRxiv
. 2023 Oct;
PMID: 37873369
More than twenty recurrent missense gain-of-function (GOF) mutations have been identified in the sodium-activated potassium (K) channel gene in patients with severe developmental and epileptic encephalopathies (DEEs), most of which...
6.
Qunies A, Spitznagel B, Du Y, Weaver C, Emmitte K
Bioorg Med Chem
. 2023 Oct;
95:117487.
PMID: 37812884
Malignant migrating partial seizure of infancy (MMPSI) is a devastating and pharmacoresistant form of infantile epilepsy. MMPSI has been linked to multiple gain-of-function (GOF) mutations in the KCNT1 gene, which...
7.
Schuss C, Vu O, Mishra N, Tough I, Du Y, Stichel J, et al.
J Med Chem
. 2023 Jun;
66(13):8745-8766.
PMID: 37339079
Positive allosteric modulators targeting the Y receptor (YR), a G protein-coupled receptor (GPCR) involved in the regulation of satiety, offer great potential in anti-obesity research. In this study, we selected...
8.
Qunies A, Mishra N, Spitznagel B, Du Y, Acuna V, Weaver C, et al.
Bioorg Med Chem Lett
. 2022 Oct;
76:129013.
PMID: 36184030
In this Letter we describe structure-activity relationship (SAR) studies conducted in five distinct regions of a new 2-amino-N-phenylacetamides series of Slack potassium channel inhibitors exemplified by recently disclosed high-throughput screening...
9.
Qunies A, Emmitte K
Pharm Pat Anal
. 2022 Apr;
11(2):45-56.
PMID: 35369761
Slack channels are sodium-activated potassium channels that are encoded by the gene. Several gain of function mutations have been linked to malignant migrating partial seizures of infancy. Quinidine is an...
10.
Qunies A, Emmitte K
Expert Opin Ther Pat
. 2021 Mar;
31(8):687-708.
PMID: 33719801
Introduction: Group II metabotropic glutamate (mGlu) receptors have emerged as an attractive potential target for the development of novel CNS therapeutics in areas such as Alzheimer's disease (AD), anxiety, cognitive...