Kuo-Hsiang Chuang
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Explore the profile of Kuo-Hsiang Chuang including associated specialties, affiliations and a list of published articles.
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Articles
57
Citations
504
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Recent Articles
1.
Liao T, Liu Y, Chen C, Wu B, Liu E, Hong S, et al.
Int J Biol Macromol
. 2025 Feb;
305(Pt 2):141003.
PMID: 39978521
4-1BB is a co-stimulatory immune checkpoint receptor that triggers CD8 T cell activation, leading to robust anti-tumor responses. Although antibodies targeting 4-1BB show promise in preclinical studies, systemic 4-1BB over-activation...
2.
Lin T, Chou P, Shen Y, Sheu M, Chuang K, Lin S, et al.
Int J Nanomedicine
. 2024 Nov;
19:10983-11002.
PMID: 39493273
Purpose: Immunotherapy emerges as a promising frontier in cancer therapy and prevention. This study investigates the capacity of tumor-antigenic nanoparticles, specifically ovalbumin-tethered spiked virus-like poly(lactic-co-glycolic acid) nanoparticles (OVA-sVLNP), to effectively...
3.
Ochirbat S, Kan T, Hsu C, Huang T, Chuang K, Chen M, et al.
Angiogenesis
. 2024 Aug;
27(4):827-843.
PMID: 39177676
Nicotine acts as an angiogenic factor by stimulating endogenous cholinergic pathways. Several subtypes of nicotinic acetylcholine receptors (nAChRs) have been demonstrated to be closely correlated to the formation and progression...
4.
Lin T, Wang K, Chuang K, Kao A, Kuo T
Taiwan J Obstet Gynecol
. 2024 Mar;
63(2):178-185.
PMID: 38485312
Objective: Endometriosis is an estrogen-dependent chronic inflammatory disease in women of reproductive age. A review of the literature revealed that cytokines and inflammatory factors are associated with endometriosis-associated infertility. Interleukin...
5.
Chen Y, Chen M, Cheng T, Tsai Y, Wang C, Chen C, et al.
J Biomed Sci
. 2023 May;
30(1):35.
PMID: 37259079
Background: Cancer-specific adoptive T cell therapy has achieved successful milestones in multiple clinical treatments. However, the commercial production of cancer-specific T cells is often hampered by laborious cell culture procedures,...
6.
Tseng H, Banerjee S, Qian B, Lai M, Wu T, Hsu T, et al.
Eur J Med Chem
. 2023 May;
256:115459.
PMID: 37172473
Monoamine oxidase A (MAO A) and heat shock protein 90 (HSP90) inhibitors have been shown to decrease the progression of glioblastoma (GBM) and other cancers. In this study, a series...
7.
Lin T, Wang K, Chuang K, Kao A, Kuo T
Taiwan J Obstet Gynecol
. 2023 Jan;
62(1):16-21.
PMID: 36720532
Objective: Research has suggested that tumor-initiating tumor stem cells are derived from normal stem cells and that tumor cells undergo progressive de-differentiation to achieve a stem cell-like state. Tumor stem...
8.
Wang C, Chen C, Wang K, Kao A, Chen Y, Lin P, et al.
Stem Cells Transl Med
. 2023 Jan;
12(1):39-53.
PMID: 36610716
Current mesenchymal stem cell (MSC) research is based on xenotransplantation of human MSCs (hMSCs) in immunodeficient mice and cannot comprehensively predict MSC repair mechanisms and immunomodulatory effects in damaged tissue....
9.
Cheng W, Lin S, Chuang K, Chen M, Ho H, Chen L, et al.
Int J Nanomedicine
. 2022 Nov;
17:5353-5374.
PMID: 36419719
Introduction: Approximately 15%~30% of breast cancers have gene amplification or overexpression of the human epidermal growth factor receptor 2 (HER2), resulting in the chemotherapy resistance, a more-aggressive phenotype and poor...
10.
Wu T, Chen M, Chen I, Chen Y, Chen C, Wang C, et al.
J Adv Res
. 2022 Jun;
46:159-171.
PMID: 35752438
Introduction: The tumor microenvironment is mainly flooded with immunosuppressive cells and inhibitory cytokines, resulting in the inability of effective immune cells to infiltrate and recognize tumors and even the loss...