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Kung-Woo Nam

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Articles 52
Citations 418
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Recent Articles
1.
Kim K, Im A, Shim K, Lee A, Kim T, Choi S, et al.
Photodermatol Photoimmunol Photomed . 2024 Nov; 40(6):e13011. PMID: 39541388
Background: Exposure to solar ultraviolet-B (UV-B) radiation significantly accelerates skin aging by inducing the expression of matrix metalloproteinases (MMPs) such as MMP-1, leading to alterations in the extracellular matrix and...
2.
Seo H, Kim S, Mahmud H, Islam M, Yoon Y, Cho H, et al.
PLoS Biol . 2022 May; 20(5):e3001648. PMID: 35639773
The continued spread of drug-resistant tuberculosis is one of the most pressing and complex challenges facing tuberculosis management worldwide. Therefore, developing a new class of drugs is necessary and urgently...
3.
Kim K, Lee J, Jeon B, Quan K, Na M, Nam K, et al.
Nutr Res Pract . 2021 Jun; 15(3):319-328. PMID: 34093973
Background/objectives: R. () has been used to treat headache, fever, and hypertension-related symptoms in Asian countries, including Korea, China, and Japan. We investigated whether dietary intake of a extract (CzE)...
4.
Lee G, Jeong H, Yang H, Seo Y, Jung E, Lee Y, et al.
Molecules . 2021 Jun; 26(10). PMID: 34068164
Astragaloside IV (AS-IV) is one of the major bio-active ingredients of huang qi which is the dried root of (a traditional Chinese medicinal plant). The pharmacological effects of AS-IV, including...
5.
Mahmud H, Seo H, Kim S, Islam M, Sultana O, Nam K, et al.
Future Med Chem . 2020 Dec; 13(3):251-267. PMID: 33295787
Tuberculosis is the leading cause of mortality among infectious diseases worldwide. Finding a new competent anti tubercular therapy is essential. We screened thousands of compounds and evaluated their efficacy against...
6.
Han K, Jung E, Kwon H, Patnaik B, Baliarsingh S, Kim W, et al.
Int J Biol Macromol . 2020 Oct; 166:45-53. PMID: 33068623
Streptococcus mutans is a gram-positive bacterium that causes tooth decay. The exopolyssacharides, mostly glucans synthesized by the bacterium are responsible for establishing pathogenic bio-films associated with dental caries disease. The...
7.
Kim N, Kim H, Lee J, Jo S, Won H, Lee G, et al.
Molecules . 2020 Jul; 25(13). PMID: 32646056
The NLRP3 (NACHT, LRR and PYD domains-containing protein 3) inflammasome has been implicated in a variety of diseases, including atherosclerosis, neurodegenerative diseases, and infectious diseases. Thus, inhibitors of NLRP3 inflammasome...
8.
Im A, Ji K, Nam K, Chae S
J Pharm Pharmacol . 2020 Jul; 72(9):1278-1286. PMID: 32618003
Objectives: Sosihotang (SSH) is an herbal medicine traditionally used against the common cold, and hepatic and gastric diseases, in Northeast Asia. In this study, we investigated whether SSH extract can...
9.
Islam M, Han C, Seo H, Kim S, Mahmud H, Nam K, et al.
Int J Antimicrob Agents . 2019 Feb; 54(1):69-74. PMID: 30807817
Due to the emergence of multidrug-resistant and extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis, new antituberculosis drugs are urgently required to improve the efficacy of current tuberculosis (TB) treatment. To...
10.
Kim S, Seo H, Mahmud H, Islam M, Kim Y, Lyu J, et al.
J Microbiol Biotechnol . 2017 Sep; 27(11):1932-1941. PMID: 28870005
DFC-2, a methyl 5-[2-(dimethylamino)ethoxy]-7,12-dioxo-7,12-dihydrodinaphtho[1,2-b:2',3'-d]furan-6-carboxylate, is reported to have antitubercular effects against . At concentrations ranging from 0.19 to 0.39 μg/ml, DFC-2 inhibited both drug-susceptible and -resistant strains of . Microarray...