Kuan-Wei Huang
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Explore the profile of Kuan-Wei Huang including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
291
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Recent Articles
11.
Huang K, Chen J, Hua T, Chu Y, Chiu T, Liu J, et al.
JACS Au
. 2022 Jan;
1(12):2315-2327.
PMID: 34977900
For using targeted covalent inhibitors (TCIs) as anticancer and antiviral drugs, we establish that the model compounds PCMPS (-chloromercuriphenyl sulfate) and PCMB (-chloromercuribenzoate) are inhibitors of the DEDDh family of...
12.
Song J, Chang C, Wu C, Dinh T, Jan J, Huang K, et al.
Proc Natl Acad Sci U S A
. 2021 Mar;
118(13).
PMID: 33753481
The CXC chemokine receptor type 4 (CXCR4) receptor and its ligand, CXCL12, are overexpressed in various cancers and mediate tumor progression and hypoxia-mediated resistance to cancer therapy. While CXCR4 antagonists...
13.
Chen C, Mao H, Yang Z, Huang K, Yan H, Rwei S
Polymers (Basel)
. 2020 Sep;
12(9).
PMID: 32899178
Bio-based unsaturated poly(butylene adipate-co-butylene itaconate) (PBABI) aliphatic copolyesters were synthesized with pentaerythritol (PE) as a modifier, observing the melting point, crystallization, and glass transition temperatures were decreased from 59.5 to...
14.
Chen C, Hsu T, Huang K, Rwei S
Polymers (Basel)
. 2020 May;
12(5).
PMID: 32438555
Unsaturated poly (butylene adipate-co-butylene itaconate) (PBABI) copolyesters were synthesized through melt polymerization composed of 1,4-butanediol (BDO), adipic acid (AA), itaconic acid (IA) and 1,2,4,5-benzenetetracarboxylic acid (BTCA) as a cross-linking modifier....
15.
Huang K, Hsu F, Qiu J, Chern G, Lee Y, Chang C, et al.
Sci Adv
. 2020 Jan;
6(3):eaax5032.
PMID: 31998834
While immunotherapy holds great promise for combating cancer, the limited efficacy due to an immunosuppressive tumor microenvironment and systemic toxicity hinder the broader application of cancer immunotherapy. Here, we report...
16.
Cheng H, Lin C, Huang K, Wang S, Lin Y, Toh S, et al.
Nucleic Acids Res
. 2018 Oct;
46(22):12166-12176.
PMID: 30357414
The three prime repair exonuclease 2 (TREX2) is an essential 3'-to-5' exonuclease that functions in cell proliferation, genome integrity and skin homeostasis maintenance. The abnormal expression level of TREX2 can...
17.
Lin C, Chen W, Chu C, Huang K, Yeh C, Cheng B, et al.
Light Sci Appl
. 2018 Sep;
5(4):e16066.
PMID: 30167160
The remarkable narrow-band emission of trivalent lanthanide-doped phosphors excited by the vacuum ultraviolet (VUV) radiation lines of Xe atoms/Xe molecules at 147/172 nm are extensively investigated in the development of...
18.
Galactose Derivative-Modified Nanoparticles for Efficient siRNA Delivery to Hepatocellular Carcinoma
Huang K, Lai Y, Chern G, Huang S, Tsai C, Sung Y, et al.
Biomacromolecules
. 2018 May;
19(6):2330-2339.
PMID: 29808997
Successful siRNA therapy requires suitable delivery systems with targeting moieties such as small molecules, peptides, antibodies, or aptamers. Galactose (Gal) residues recognized by the asialoglycoprotein receptor (ASGPR) can serve as...
19.
Huang K, Liu T, Liang R, Chu L, Cheng H, Chu J, et al.
PLoS Biol
. 2018 May;
16(5):e2005653.
PMID: 29734329
Three prime repair exonuclease 1 (TREX1) is an essential exonuclease in mammalian cells, and numerous in vivo and in vitro data evidenced its participation in immunity regulation and in genotoxicity...
20.
Lin T, Huang K, Liu C, Chang Y, Lin W, Yang T, et al.
Oncotarget
. 2018 Apr;
9(24):17210-17219.
PMID: 29682217
Leptin is a peptide hormone that has been characterized as the ligand of leptin receptor (). The observation of leptin secretion and leptin receptor expression beyond the normal tissues suggests...