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Chun-I Tu

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Recent Articles
1.
Huang K, Wu C, Toh S, Liu T, Tu C, Lin Y, et al.
Nucleic Acids Res . 2023 Oct; 51(21):11927-11940. PMID: 37870446
In various autoimmune diseases, dysfunctional TREX1 (Three prime Repair Exonuclease 1) leads to accumulation of endogenous single-stranded DNA (ssDNA), double-stranded DNA (dsDNA) and DNA/RNA hybrids in the cytoplasm and triggers...
2.
Huang K, Chen J, Hua T, Chu Y, Chiu T, Liu J, et al.
JACS Au . 2022 Jan; 1(12):2315-2327. PMID: 34977900
For using targeted covalent inhibitors (TCIs) as anticancer and antiviral drugs, we establish that the model compounds PCMPS (-chloromercuriphenyl sulfate) and PCMB (-chloromercuribenzoate) are inhibitors of the DEDDh family of...