Kristyna Holzerova
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Explore the profile of Kristyna Holzerova including associated specialties, affiliations and a list of published articles.
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10
Citations
53
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Recent Articles
1.
Benak D, Sevcikova A, Holzerova K, Hlavackova M
Front Cell Dev Biol
. 2025 Jan;
12:1500394.
PMID: 39744011
Fat mass and obesity-associated (FTO) protein, a key enzyme integral to the dynamic regulation of epitranscriptomic modifications in RNAs, significantly influences crucial RNA lifecycle processes, including splicing, export, decay, and...
2.
Benak D, Holzerova K, Kolar F, Chalupova M, Hlavackova M
Front Physiol
. 2024 Oct;
15:1462014.
PMID: 39469441
Fasting is a common dietary intervention known for its protective effects against metabolic and cardiovascular diseases. While its effects are mostly systemic, understanding tissue-specific changes in the heart is crucial...
3.
Alanova P, Alan L, Opletalova B, Bohuslavova R, Abaffy P, Matejkova K, et al.
Acta Physiol (Oxf)
. 2024 Jul;
240(9):e14202.
PMID: 39016532
Aim: The transcriptional factor HIF-1α is recognized for its contribution to cardioprotection against acute ischemia/reperfusion injury. Adaptation to chronic hypoxia (CH) is known to stabilize HIF-1α and increase myocardial ischemic...
4.
Sedlar A, Vrbata D, Pokorna K, Holzerova K, cerveny J, Kockova O, et al.
J Med Chem
. 2024 Jun;
67(11):9214-9226.
PMID: 38829964
Pulmonary hypertension is a cardiovascular disease with a low survival rate. The protein galectin-3 (Gal-3) binding β-galactosides of cellular glycoproteins plays an important role in the onset and development of...
5.
Benak D, Holzerova K, Hrdlicka J, Kolar F, Olsen M, Karelson M, et al.
RNA Biol
. 2024 Feb;
21(1):1-14.
PMID: 38326277
Cardiac tolerance to ischaemia can be increased by dietary interventions such as fasting, which is associated with significant changes in myocardial gene expression. Among the possible mechanisms of how gene...
6.
Pokorna Z, Jirkovsky E, Hlavackova M, Jansova H, Jirkovska A, Lencova-Popelova O, et al.
Clin Sci (Lond)
. 2019 Aug;
133(16):1827-1844.
PMID: 31409729
Although proteasome inhibitors (PIs) are modern targeted anticancer drugs, they have been associated with a certain risk of cardiotoxicity and heart failure (HF). Recently, PIs have been combined with anthracyclines...
7.
Kohutova J, Elsnicova B, Holzerova K, Neckar J, Sebesta O, Jezkova J, et al.
Front Endocrinol (Lausanne)
. 2019 Feb;
9:789.
PMID: 30740090
Remodeling of the cellular distribution of gap junctions formed mainly by connexin-43 (Cx43) can be related to the increased incidence of cardiac arrhythmias. It has been shown that adaptation to...
8.
Micova P, Klevstig M, Holzerova K, Vecka M, Zurmanova J, Neckar J, et al.
Can J Physiol Pharmacol
. 2017 May;
95(8):920-927.
PMID: 28459156
Adaptation to chronic intermittent hypoxia (CIH) is associated with reactive oxygen species (ROS) generation implicated in the improved cardiac tolerance against acute ischemia-reperfusion injury. Phospholipases A (PLAs) play an important...
9.
Alanova P, Chytilova A, Neckar J, Hrdlicka J, Micova P, Holzerova K, et al.
J Appl Physiol (1985)
. 2017 Feb;
122(6):1452-1461.
PMID: 28209739
Chronic hypoxia and exercise are natural stimuli that confer sustainable cardioprotection against ischemia-reperfusion (I/R) injury, but it is unknown whether they can act in synergy to enhance ischemic resistance. Inflammatory...
10.
Micova P, Hahnova K, Hlavackova M, Elsnicova B, Chytilova A, Holzerova K, et al.
Mol Cell Biochem
. 2016 Oct;
423(1-2):151-163.
PMID: 27686454
Cardiac resistance against acute ischemia/reperfusion (I/R) injury can be enhanced by adaptation to chronic intermittent hypoxia (CIH), but the changes at the molecular level associated with this adaptation are still...