Kristrun R Benediktsdottir
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Explore the profile of Kristrun R Benediktsdottir including associated specialties, affiliations and a list of published articles.
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26
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3945
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Recent Articles
1.
Stacey S, Kehr B, Gudmundsson J, Zink F, Jonasdottir A, Gudjonsson S, et al.
Hum Mol Genet
. 2016 Jan;
25(5):1008-18.
PMID: 26740556
Transcriptional and splicing anomalies have been observed in intron 8 of the CASP8 gene (encoding procaspase-8) in association with cutaneous basal-cell carcinoma (BCC) and linked to a germline SNP rs700635....
2.
Stacey S, Helgason H, Gudjonsson S, Thorleifsson G, Zink F, Sigurdsson A, et al.
Nat Commun
. 2015 Apr;
6:6825.
PMID: 25855136
In an ongoing screen for DNA sequence variants that confer risk of cutaneous basal cell carcinoma (BCC), we conduct a genome-wide association study (GWAS) of 24,988,228 SNPs and small indels...
3.
Stacey S, Sulem P, Gudbjartsson D, Jonasdottir A, Thorleifsson G, Gudjonsson S, et al.
Hum Mol Genet
. 2014 Jan;
23(11):3045-53.
PMID: 24403052
To search for new sequence variants that confer risk of cutaneous basal cell carcinoma (BCC), we conducted a genome-wide association study of 38.5 million single nucleotide polymorphisms (SNPs) and small...
4.
Iles M, Law M, Stacey S, Han J, Fang S, Pfeiffer R, et al.
Nat Genet
. 2013 Mar;
45(4):428-32, 432e1.
PMID: 23455637
We report the results of an association study of melanoma that is based on the genome-wide imputation of the genotypes of 1,353 cases and 3,566 controls of European origin conducted...
5.
Gudmundsson J, Sulem P, Gudbjartsson D, Masson G, Agnarsson B, Benediktsdottir K, et al.
Nat Genet
. 2012 Oct;
44(12):1326-9.
PMID: 23104005
In Western countries, prostate cancer is the most prevalent cancer of men and one of the leading causes of cancer-related death in men. Several genome-wide association studies have yielded numerous...
6.
Rafnar T, Gudbjartsson D, Sulem P, Jonasdottir A, Sigurdsson A, Jonasdottir A, et al.
Nat Genet
. 2011 Oct;
43(11):1104-7.
PMID: 21964575
Ovarian cancer causes more deaths than any other gynecologic malignancy in developed countries. Sixteen million sequence variants, identified through whole-genome sequencing of 457 Icelanders, were imputed to 41,675 Icelanders genotyped...
7.
Stacey S, Sulem P, Jonasdottir A, Masson G, Gudmundsson J, Gudbjartsson D, et al.
Nat Genet
. 2011 Sep;
43(11):1098-103.
PMID: 21946351
To identify new risk variants for cutaneous basal cell carcinoma, we performed a genome-wide association study of 16 million SNPs identified through whole-genome sequencing of 457 Icelanders. We imputed genotypes...
8.
Gudmundsson J, Besenbacher S, Sulem P, Gudbjartsson D, Olafsson I, Arinbjarnarson S, et al.
Sci Transl Med
. 2010 Dec;
2(62):62ra92.
PMID: 21160077
Measuring serum levels of the prostate-specific antigen (PSA) is the most common screening method for prostate cancer. However, PSA levels are affected by a number of factors apart from neoplasia....
9.
Kong A, Steinthorsdottir V, Masson G, Thorleifsson G, Sulem P, Besenbacher S, et al.
Nature
. 2009 Dec;
462(7275):868-74.
PMID: 20016592
Effects of susceptibility variants may depend on from which parent they are inherited. Although many associations between sequence variants and human traits have been discovered through genome-wide associations, the impact...
10.
Gudmundsson J, Sulem P, Gudbjartsson D, Blondal T, Gylfason A, Agnarsson B, et al.
Nat Genet
. 2009 Sep;
41(10):1122-6.
PMID: 19767754
We report a prostate cancer genome-wide association follow-on study. We discovered four variants associated with susceptibility to prostate cancer in several European populations: rs10934853[A] (OR = 1.12, P = 2.9...