Julius Gudmundsson
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Explore the profile of Julius Gudmundsson including associated specialties, affiliations and a list of published articles.
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58
Citations
6403
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Recent Articles
1.
Ivarsdottir E, Gudmundsson J, Tragante V, Sveinbjornsson G, Kristmundsdottir S, Stacey S, et al.
Nat Genet
. 2024 Oct;
56(11):2422-2433.
PMID: 39472694
Discovery of cancer risk variants in the sequence of the germline genome can shed light on carcinogenesis. Here we describe gene burden association analyses, aggregating rare missense and loss of...
2.
Stankovic S, Shekari S, Huang Q, Gardner E, Ivarsdottir E, Owens N, et al.
Nature
. 2024 Sep;
633(8030):608-614.
PMID: 39261734
Human genetic studies of common variants have provided substantial insight into the biological mechanisms that govern ovarian ageing. Here we report analyses of rare protein-coding variants in 106,973 women from...
3.
Saevarsdottir S, Bjarnadottir K, Markusson T, Berglund J, Olafsdottir T, Halldorsson G, et al.
Nat Commun
. 2024 Jul;
15(1):5748.
PMID: 38982041
Autoimmune thyroid disease (AITD) is a common autoimmune disease. In a GWAS meta-analysis of 110,945 cases and 1,084,290 controls, 290 sequence variants at 225 loci are associated with AITD. Of...
4.
Jensson B, Arnadottir G, Katrinardottir H, Fridriksdottir R, Helgason H, Oddsson A, et al.
N Engl J Med
. 2023 Nov;
389(19):1741-1752.
PMID: 37937776
Background: In 2021, the American College of Medical Genetics and Genomics (ACMG) recommended reporting actionable genotypes in 73 genes associated with diseases for which preventive or therapeutic measures are available....
5.
Stacey S, Zink F, Halldorsson G, Stefansdottir L, Gudjonsson S, Einarsson G, et al.
Nat Genet
. 2023 Nov;
55(12):2149-2159.
PMID: 37932435
Clonal hematopoiesis (CH) arises when a substantial proportion of mature blood cells is derived from a single hematopoietic stem cell lineage. Using whole-genome sequencing of 45,510 Icelandic and 130,709 UK...
6.
Holm H, Ivarsdottir E, Olafsdottir T, Thorolfsdottir R, Eythorsson E, Norland K, et al.
Commun Med (Lond)
. 2023 Jul;
3(1):94.
PMID: 37414856
Background: Persistent symptoms are common after SARS-CoV-2 infection but correlation with objective measures is unclear. Methods: We invited all 3098 adults who tested SARS-CoV-2 positive in Iceland before October 2020...
7.
Zhou W, Brumpton B, Kabil O, Gudmundsson J, Thorleifsson G, Weinstock J, et al.
Nat Commun
. 2021 Dec;
12(1):7354.
PMID: 34916535
No abstract available.
8.
Mikaelsdottir E, Thorleifsson G, Stefansdottir L, Halldorsson G, Sigurdsson J, Lund S, et al.
Commun Biol
. 2021 Sep;
4(1):1132.
PMID: 34580418
Platelets play an important role in hemostasis and other aspects of vascular biology. We conducted a meta-analysis of platelet count GWAS using data on 536,974 Europeans and identified 577 independent...
9.
Olafsdottir T, Stacey S, Sveinbjornsson G, Thorleifsson G, Norland K, Sigurgeirsson B, et al.
Cancer Res
. 2021 Feb;
81(8):1954-1964.
PMID: 33602785
The success of genome-wide association studies (GWAS) in identifying common, low-penetrance variant-cancer associations for the past decade is undisputed. However, discovering additional high-penetrance cancer mutations in unknown cancer predisposing genes...
10.
Zhou W, Brumpton B, Kabil O, Gudmundsson J, Thorleifsson G, Weinstock J, et al.
Nat Commun
. 2020 Aug;
11(1):3981.
PMID: 32769997
Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis at 22.4 million genetic markers...