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Kristofer Ahlqvist

Explore the profile of Kristofer Ahlqvist including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Saamarthy K, Daams R, Sime W, Persson C, Chygorin E, Ahlqvist K, et al.
Br J Pharmacol . 2025 Feb; PMID: 39943627
Background And Purpose: Malignant melanoma is the most lethal form of skin cancer, characterised by a poor survival rate. One of the key factors driving the aggressive growth of melanoma...
2.
Saamarthy K, Ahlqvist K, Daams R, Balagunaseelan N, Rinaldo-Matthis A, Kazi J, et al.
BMC Cancer . 2024 Jan; 24(1):103. PMID: 38238702
Molecular targeted therapy using a drug that suppresses the growth and spread of cancer cells via inhibition of a specific protein is a foundation of precision medicine and treatment. High...
3.
Ke H, Masoumi K, Ahlqvist K, Seckl M, Rydell-Tormanen K, Massoumi R
Sci Rep . 2016 Apr; 6:23987. PMID: 27035511
The canonical Wnt signaling can be silenced either through β-catenin-mediated ubiquitination and degradation or through phosphorylation of Tcf and Lef by nemo-like kinase (NLK). In the present study, we generated...
4.
Pannem R, Dorn C, Ahlqvist K, Bosserhoff A, Hellerbrand C, Massoumi R
Carcinogenesis . 2013 Oct; 35(2):461-8. PMID: 24104553
Posttranslational modification of different proteins via direct ubiquitin attachment is vital for mediating various cellular processes. Cylindromatosis (CYLD), a deubiquitination enzyme, is able to cleave the polyubiquitin chains from the...
5.
Liang G, Ahlqvist K, Pannem R, Posern G, Massoumi R
PLoS One . 2011 May; 6(5):e19613. PMID: 21573132
Tumor suppressor gene CYLD is a deubiquitinating enzyme which negatively regulates various signaling pathways by removing the lysine 63-linked polyubiquitin chains from several specific substrates. Loss of CYLD in different...