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Kristina Solorio-Kirpichyan

Explore the profile of Kristina Solorio-Kirpichyan including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Bhaduri S, Braza M, Stanchev S, Tauber M, Al-Bawab R, Liu L, et al.
J Biol Chem . 2025 Feb; 301(3):108275. PMID: 39922490
Rhomboid proteases are ubiquitous intramembrane serine proteases that can cleave transmembrane substrates within lipid bilayers. They exhibit many and diverse functions, such as but not limited to, growth factor signaling,...
2.
Solorio-Kirpichyan K, Fan X, Golovenko D, Korostelev A, Yan N, Korennykh A
PNAS Nexus . 2024 Dec; 3(12):pgae528. PMID: 39618511
GCN2 is a conserved receptor kinase activating the integrated stress response (ISR) in eukaryotic cells. The ISR kinases detect accumulation of stress molecules and reprogram translation from basal tasks to...
3.
Bhaduri S, Braza M, Stanchev S, Tauber M, Al-Bawab R, Liu L, et al.
bioRxiv . 2024 Oct; PMID: 39415989
Rhomboid proteases are ubiquitous intramembrane serine proteases that can cleave transmembrane substrates within lipid bilayers. They exhibit many and diverse functions, such as but not limited to, growth factor signaling,...
4.
Solorio-Kirpichyan K, Fan X, Golovenko D, Korostelev A, Yan N, Korennykh A
bioRxiv . 2024 May; PMID: 38712127
Significance Statement: Regulation of protein synthesis (translation) is a central mechanism by which eukaryotic cells adapt to stressful conditions. In starving cells, this translational adaptation is achieved via the receptor...
5.
Du J, Estrella M, Solorio-Kirpichyan K, Jeffrey P, Korennykh A
Proc Natl Acad Sci U S A . 2022 Jun; 119(26):e2200923119. PMID: 35733246
All kingdoms of life produce essential nicotinamide dinucleotide NADP(H) using NAD kinases (NADKs). A panel of published NADK structures from bacteria, eukaryotic cytosol, and yeast mitochondria revealed similar tetrameric enzymes....
6.
Chitrakar A, Solorio-Kirpichyan K, Prangley E, Rath S, Du J, Korennykh A
Proc Natl Acad Sci U S A . 2021 Nov; 118(46). PMID: 34772806
Double-stranded RNA (dsRNA), a hallmark viral material that activates antiviral interferon (IFN) responses, can appear in human cells also in the absence of viruses. We identify phosphorothioate DNAs (PS DNAs)...