Kristian E Swearingen
Overview
Explore the profile of Kristian E Swearingen including associated specialties, affiliations and a list of published articles.
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25
Citations
581
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Recent Articles
1.
Widespread release of translational repression across Plasmodium's host-to-vector transmission event
Rios K, McGee J, Sebastian A, Gedara S, Moritz R, Feric M, et al.
PLoS Pathog
. 2025 Jan;
21(1):e1012823.
PMID: 39777415
Malaria parasites must respond quickly to environmental changes, including during their transmission between mammalian and mosquito hosts. Therefore, female gametocytes proactively produce and translationally repress mRNAs that encode essential proteins...
2.
Nagar R, Garcia Castillo S, Pinzon-Ortiz M, Patray S, Coppi A, Kanatani S, et al.
J Biol Chem
. 2024 Jul;
300(8):107557.
PMID: 39002668
Glycosylphosphatidylinositol (GPI) anchor protein modification in Plasmodium species is well known and represents the principal form of glycosylation in these organisms. The structure and biosynthesis of GPI anchors of Plasmodium...
3.
Nagar R, Garcia Castillo S, Pinzon-Ortiz M, Patray S, Coppi A, Kanatani S, et al.
bioRxiv
. 2024 Jun;
PMID: 38826328
Glycosylphosphatidylinositol (GPI) anchor protein modification in species is well known and represents the principal form of glycosylation in these organisms. The structure and biosynthesis of GPI anchors of spp. has...
4.
Rios K, McGee J, Sebastian A, Moritz R, Feric M, Absalon S, et al.
bioRxiv
. 2024 Feb;
PMID: 38352447
Malaria parasites must be able to respond quickly to changes in their environment, including during their transmission between mammalian hosts and mosquito vectors. Therefore, before transmission, female gametocytes proactively produce...
5.
Jennison C, Armstrong J, Dankwa D, Hertoghs N, Kumar S, Abatiyow B, et al.
Mol Microbiol
. 2023 Jun;
121(3):394-412.
PMID: 37314965
Plasmodium parasites, the eukaryotic pathogens that cause malaria, feature three distinct invasive forms tailored to the host environment they must navigate and invade for life cycle progression. One conserved feature...
6.
Lindner S, Swearingen K, Shears M, Sebastian A, Walker M, Vrana E, et al.
Nat Commun
. 2022 Jan;
13(1):283.
PMID: 34992211
No abstract available.
7.
Kumar S, Haile M, Hoopmann M, Tran L, Michaels S, Morrone S, et al.
mBio
. 2021 Nov;
12(6):e0257521.
PMID: 34724830
Gametocytes of the malaria parasite are taken up by the mosquito vector with an infectious blood meal, representing a critical stage for parasite transmission. Calcium-independent protein kinases (CDPKs) play key...
8.
Steel R, Vigdorovich V, Dambrauskas N, Wilder B, Arredondo S, Goswami D, et al.
Sci Rep
. 2021 Jun;
11(1):11328.
PMID: 34059712
Following their inoculation by the bite of an infected Anopheles mosquito, the malaria parasite sporozoite forms travel from the bite site in the skin into the bloodstream, which transports them...
9.
Searle B, Swearingen K, Barnes C, Schmidt T, Gessulat S, Kuster B, et al.
Nat Commun
. 2020 Mar;
11(1):1548.
PMID: 32214105
Data-independent acquisition approaches typically rely on experiment-specific spectrum libraries, requiring offline fractionation and tens to hundreds of injections. We demonstrate a library generation workflow that leverages fragmentation and retention time...
10.
Lindner S, Swearingen K, Shears M, Walker M, Vrana E, Hart K, et al.
Nat Commun
. 2019 Nov;
10(1):4964.
PMID: 31673027
Plasmodium sporozoites are transmitted from infected mosquitoes to mammals, and must navigate the host skin and vasculature to infect the liver. This journey requires distinct proteomes. Here, we report the...