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Krista den Ouden

Explore the profile of Krista den Ouden including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 994
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Recent Articles
1.
Besseling P, Szymczyk W, Teraa M, Toorop R, Wu D, Driessen R, et al.
Adv Healthc Mater . 2024 Mar; 13(17):e2303888. PMID: 38451476
Current vascular access options require frequent interventions. In situ tissue engineering (TE) may overcome these limitations by combining the initial success of synthetic grafts with long-term advantages of autologous vessels...
2.
Besseling P, Krebber M, Fledderus J, Teraa M, den Ouden K, van de Kaa M, et al.
APL Bioeng . 2023 May; 7(2):026107. PMID: 37234843
Vascular tissue engineering encompasses a single-step approach with a wide adaptive potential and true off-the-shelf availability for vascular grafts. However, a synchronized balance between breakdown of the scaffold material and...
3.
van Rhijn-Brouwer F, Gremmels H, den Ouden K, Teraa M, Fledderus J, Verhaar M
Stem Cells Dev . 2022 Feb; 31(7-8):176-180. PMID: 35152731
Effective treatments for chronic limb-threatening ischemia are lacking. (Pre)clinical studies on administration of bone marrow (BM) mononuclear cells (MNCs) and BM-derived mesenchymal stromal cells (MSCs) have shown variable results and...
4.
Deddens J, Vrijsen K, Colijn J, Oerlemans M, Metz C, van der Vlist E, et al.
J Cardiovasc Transl Res . 2016 Jul; 9(4):291-301. PMID: 27383837
Plasma-circulating microRNAs have been implicated as novel early biomarkers for myocardial infarction (MI) due to their high specificity for cardiac injury. For swift clinical translation of this potential biomarker, it...
5.
Slaats G, Wheway G, Foletto V, Szymanska K, van Balkom B, Logister I, et al.
J Cell Sci . 2015 Nov; 128(24):4550-9. PMID: 26546361
To investigate the contribution of ion channels to ciliogenesis, we carried out a small interfering RNA (siRNA)-based reverse genetics screen of all ion channels in the mouse genome in murine...
6.
Slaats G, Saldivar J, Bacal J, Zeman M, Kile A, Hynes A, et al.
J Clin Invest . 2015 Aug; 125(9):3657-66. PMID: 26301811
Juvenile ciliopathy syndromes that are associated with renal cysts and premature renal failure are commonly the result of mutations in the gene encoding centrosomal protein CEP290. In addition to centrosomes...
7.
Gremmels H, Teraa M, Quax P, den Ouden K, Fledderus J, Verhaar M
Mol Ther . 2014 Sep; 22(11):1960-70. PMID: 25174586
Critical limb ischemia (CLI) is often poorly treatable by conventional management and alternatives such as autologous cell therapy are increasingly investigated. Whereas previous studies showed a substantial impairment of neovascularization...
8.
Feyen D, Gaetani R, Liu J, Noort W, Martens A, den Ouden K, et al.
Cardiovasc Res . 2013 Apr; 99(1):83-91. PMID: 23554461
Aims: One of the main limitations for an effective cell therapy for the heart is the poor cell engraftment after implantation, which is partly due to a large percentage of...
9.
van Balkom B, de Jong O, Smits M, Brummelman J, den Ouden K, de Bree P, et al.
Blood . 2013 Mar; 121(19):3997-4006, S1-15. PMID: 23532734
Signaling between endothelial cells, endothelial progenitor cells, and stromal cells is crucial for the establishment and maintenance of vascular integrity and involves exosomes, among other signaling pathways. Exosomes are important...
10.
Arslan F, Smeets M, Buttari B, Profumo E, Rigano R, Akeroyd L, et al.
J Mol Cell Cardiol . 2013 Jan; 56:116-28. PMID: 23274064
Decreased haptoglobin (Hp) functionality due to allelic variations is associated with worsened outcome in patients after myocardial infarction (MI). However, mechanisms through which haptoglobin deficiency impairs cardiac repair remain to...