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Krishnadas Nandakumar

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Articles 57
Citations 346
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Recent Articles
1.
John J, Das S, Kunnath A, Mudgal J, Nandakumar K
Metab Brain Dis . 2025 Mar; 40(3):151. PMID: 40085284
 The cognitive alterations observed in individuals undergoing cancer treatments have garnered more attention recently. Chemotherapy can reduce nicotinamide adenine dinucleotide (NAD+) levels by inhibiting nicotinamide phosphoribosyl transferase (NAMPT). This reduction...
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Palacharla V, Nirogi R, Kumar N, Nandakumar K
Eur J Drug Metab Pharmacokinet . 2024 Dec; 50(2):119-135. PMID: 39724218
Objective: The objective of this study was to determine the apparent intrinsic clearance (Cl) and fraction unbound in human liver microsomes (f) of 86 marketed central nervous system (CNS) drugs...
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Mili A, Birangal S, Giridhar J, Nandakumar K, Lobo R
BMC Chem . 2024 Dec; 18(1):241. PMID: 39696683
PI3K-α mutation plays a critical role in cancer development, notably in breast cancer, particularly within HR + /HER2- subtypes. These mutations drive tumor growth and survival by activating the PI3K/AKT/mTOR...
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Soman S, Kulkarni S, John J, Vineeth P, Ahmad S, George S, et al.
Int J Pharm . 2024 Sep; 665:124665. PMID: 39236772
Stimuli-responsive nanoplatforms have been popular in controlled drug delivery research because of their ability to differentiate the tumor microenvironment from the normal tissue environment in a spatiotemporally controllable manner. The...
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Bilgundi K, Viswanatha G, Purushottam K, John J, Kamath A, Kishore A, et al.
Nutr Res . 2024 Jul; 128:82-93. PMID: 39067112
This study aimed to investigate the effects of prenatal docosahexaenoic acid (DHA) supplementation on pregnancy outcomes through a systematic review and meta-analysis. We hypothesized that prenatal DHA intake through supplements...
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Samant C, Kale R, Pai K, Nandakumar K, Bhonde M
Biochem Biophys Res Commun . 2024 Jul; 729:150348. PMID: 38986260
Adaptive resistance to conventional and targeted therapies remains one of the major obstacles in the effective management of cancer. Aberrant activation of key signaling mechanisms plays a pivotal role in...
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Jannapu Reddy S, Mutalik S, Viswanatha G, Kumar G, John J, Chamallamudi M, et al.
Pharm Nanotechnol . 2024 May; 13(1):212-238. PMID: 38757164
The rise in global cancer burden, notably breast cancer, emphasizes the need to address chemotherapy-induced cognitive impairment, also known as chemobrain. Although chemotherapy drugs are effective against cancer, they can...
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Rabade A, Viswanatha G, Nandakumar K, Kishore A
Inflammopharmacology . 2024 Apr; 32(3):1759-1775. PMID: 38581640
Aim: This study was aimed to assess the efficacy and safety of two oral Symptomatic Slow Acting Drugs for Osteoarthritis (SYSADOAs)-Glucosamine Sulfate, Chondroitin Sulfate, and their combination regimen in the...
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Begum F, Nandakumar K, Shenoy R
3 Biotech . 2024 Apr; 14(4):124. PMID: 38566928
Cases of diabetes are significantly increasing year by year, attracting the attention of medical professionals and researchers to focus on diabetes and its underlying complications. One among such are diabetic...