Krishna P L Bhat
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Explore the profile of Krishna P L Bhat including associated specialties, affiliations and a list of published articles.
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18
Citations
1375
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Recent Articles
11.
Cheng P, Wang J, Waghmare I, Sartini S, Coviello V, Zhang Z, et al.
Cancer Res
. 2016 Aug;
76(24):7219-7230.
PMID: 27569208
Glioma stem-like cells (GSC) with tumor-initiating activity orchestrate the cellular hierarchy in glioblastoma and engender therapeutic resistance. Recent work has divided GSC into two subtypes with a mesenchymal (MES) GSC...
12.
Kim S, Joshi K, Ezhilarasan R, Myers T, Siu J, Gu C, et al.
Stem Cell Reports
. 2015 Jan;
4(2):226-38.
PMID: 25601206
Glioblastoma (GBM)-derived tumorigenic stem-like cells (GSCs) may play a key role in therapy resistance. Previously, we reported that the mitotic kinase MELK binds and phosphorylates the oncogenic transcription factor FOXM1...
13.
Zadeh G, Bhat K, Aldape K
Cancer Cell
. 2013 Oct;
24(4):403-4.
PMID: 24135276
EGFRvIII, a mutated form of EGFR, plays a prominent role in tumorigenesis, but the underlying mechanisms have remained elusive. In this issue of Cancer Cell, Weiss and colleagues implicate phosphorylation...
14.
Bhat K, Balasubramaniyan V, Vaillant B, Ezhilarasan R, Hummelink K, Hollingsworth F, et al.
Cancer Cell
. 2013 Sep;
24(3):331-46.
PMID: 23993863
Despite extensive study, few therapeutic targets have been identified for glioblastoma (GBM). Here we show that patient-derived glioma sphere cultures (GSCs) that resemble either the proneural (PN) or mesenchymal (MES)...
15.
Bhat K, Aldape K
Cancer Discov
. 2013 Jul;
3(7):726-7.
PMID: 23847350
In this issue of Cancer Discovery, Dominguez and colleagues identify diacylglycerol kinase alpha (DGKα), an enzyme that converts the membrane lipid diacylglycerol to phosphatidic acid, as a central node upstream...
16.
Bhat K, Salazar K, Balasubramaniyan V, Wani K, Heathcock L, Hollingsworth F, et al.
Genes Dev
. 2011 Dec;
25(24):2594-609.
PMID: 22190458
Recent molecular classification of glioblastoma (GBM) has shown that patients with a mesenchymal (MES) gene expression signature exhibit poor overall survival and treatment resistance. Using regulatory network analysis of available...
17.
Bhat K, Pezzuto J
Ann N Y Acad Sci
. 2002 Jun;
957:210-29.
PMID: 12074974
Cancer chemopreventive agents are designed to reduce the incidence of tumorigenesis by intervening at one or more stages of carcinogenesis. Recently, resveratrol, a natural product found in the diet of...
18.
Burdette J, Liu J, Lantvit D, Lim E, Booth N, Bhat K, et al.
J Nutr
. 2002 Jan;
132(1):27-30.
PMID: 11773503
Studies were conducted using an ovariectomized rat model to determine the estrogenic and antiestrogenic activity of Trifolium pratense L. (red clover) extracts. A red clover extract, standardized to contain 15%...