Krishna Kurthkoti
Overview
Explore the profile of Krishna Kurthkoti including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
286
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Recent Articles
1.
Salini S, Muralikrishnan B, Bhat S, Ghate S, Rao R, Kumar R, et al.
Microb Pathog
. 2023 Oct;
185:106384.
PMID: 37838146
Mycobacterium tuberculosis is a leading cause of human mortality worldwide, and the emergence of drug-resistant strains demands the discovery of new classes of antimycobacterial that can be employed in the...
2.
Gopi Reji J, K Edison L, Raghunandanan S, Pushparajan A, Kurthkoti K, Ajay Kumar R
J Antibiot (Tokyo)
. 2023 Oct;
76(12):720-727.
PMID: 37821540
Mycobacterium tuberculosis is exposed to diverse stresses inside the host during dormancy. Meanwhile, many metabolic and transcriptional regulatory changes occur, resulting in physiological modifications that help M. tuberculosis to adapt...
3.
Rao R, Ghate S, Shastry R, Kurthkoti K, Suravajhala P, Patil P, et al.
Microb Pathog
. 2022 Dec;
174:105953.
PMID: 36529286
Despite a million infections every year and an estimated one billion people at risk, scrub typhus is regarded as a neglected tropical disease. The causative bacterium Orientia tsutsugamushi, a member...
4.
Salini S, Bhat S, Naz S, Natesh R, Kumar R, Nandicoori V, et al.
Antimicrob Agents Chemother
. 2022 Feb;
66(3):e0177321.
PMID: 35156855
Applying antibiotics to susceptible bacterial cultures generates a minor population of persisters that remain susceptible to antibiotics but can endure them for extended periods. Recent reports suggest that antibiotic persisters...
5.
Kurthkoti K, Kumar P, Sang P, Varshney U
Future Med Chem
. 2020 Feb;
12(4):339-355.
PMID: 32031026
Infectious diseases continue to be a major cause of human mortality. With the emergence of drug resistance, diseases that were long thought to have been curable by antibiotics are resurging....
6.
Kurthkoti K, Amin H, Marakalala M, Ghanny S, Subbian S, Sakatos A, et al.
mBio
. 2017 Aug;
8(4).
PMID: 28811344
This study was conducted to investigate the role of iron deprivation in the persistence of We present evidence of iron restriction in human necrotic granulomas and demonstrate that under iron...
7.
Xiong X, Kurthkoti K, Chang K, Li J, Ren X, Ni J, et al.
PLoS Pathog
. 2016 Nov;
12(11):e1006034.
PMID: 27893816
microRNAs are endogenous small regulatory RNAs that modulate myriad biological processes by repressing target gene expression in a sequence-specific manner. Here we show that the conserved miRNA miR-34 regulates innate...
8.
Xiong X, Vogler G, Kurthkoti K, Samsonova A, Zhou R
PLoS Genet
. 2015 Aug;
11(8):e1005475.
PMID: 26308709
microRNAs (miRNAs) are a class of endogenous regulatory RNAs that play a key role in myriad biological processes. Upon transcription, primary miRNA transcripts are sequentially processed by Drosha and Dicer...
9.
Kurthkoti K, Tare P, Paitchowdhury R, Gowthami V, Garcia M, Colangeli R, et al.
Mol Microbiol
. 2015 Aug;
98(5):864-77.
PMID: 26268801
Emerging evidence indicates that precise regulation of iron (Fe) metabolism and maintenance of Fe homeostasis in Mycobacterium tuberculosis (Mtb) are essential for its survival and proliferation in the host. IdeR...
10.
Xiong X, Kurthkoti K, Chang K, Lichinchi G, De N, Schneemann A, et al.
Proc Natl Acad Sci U S A
. 2013 Sep;
110(41):16520-5.
PMID: 24067655
RNAi is an evolutionarily conserved gene regulatory process that operates in a wide variety of organisms. During RNAi, long double-stranded RNA precursors are processed by Dicer proteins into ∼21-nt siRNAs....