Krishan Gupta
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Explore the profile of Krishan Gupta including associated specialties, affiliations and a list of published articles.
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19
Citations
104
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Recent Articles
1.
Zhu B, Gupta K, Cui K, Wang B, Malovichko M, Han X, et al.
bioRxiv
. 2024 Sep;
PMID: 39253478
Rationale: Low density cholesterol receptor (LDLR) in the liver is critical for the clearance of low-density lipoprotein cholesterol (LDL-C) in the blood. In atherogenic conditions, proprotein convertase subtilisin/kexin 9 (PCSK9)...
2.
Mohanty S, Maryam S, Gautam V, Mittal A, Gupta K, Arora R, et al.
Brief Funct Genomics
. 2022 Dec;
22(3):281-290.
PMID: 36542133
Odorant receptors (ORs) obey mutual exclusivity and monoallelic mode of expression. Efforts are ongoing to decipher the molecular mechanism that drives the 'one-neuron-one-receptor' rule of olfaction. Recently, single-cell profiling of...
3.
Gupta K, Wang G, Zhang S, Gao X, Zheng R, Zhang Y, et al.
Sci Adv
. 2022 Dec;
8(49):eabk2246.
PMID: 36475785
Multiple recent studies revealed stripes as an architectural feature of three-dimensional chromatin and found stripes connected to epigenetic regulation of transcription. Whereas a couple of tools are available to define...
4.
Porwal K, Porwal M, Ibrahim M, Ramaswamykanive H, Gupta K, Mathur M, et al.
Cureus
. 2022 Jun;
14(5):e24744.
PMID: 35676997
Acute mitral regurgitation (MR) is a life-threatening condition presenting with severe decompensated heart failure due to sudden retrograde blood flow into the left atrium. The causes are broadly classified into...
5.
Gupta K, Yadav P, Maryam S, Ahuja G, Sengupta D
J Mol Biol
. 2021 Aug;
433(19):167179.
PMID: 34339725
Age-dependent dysregulation of transcription regulatory machinery triggers modulations in the gene expression levels leading to the decline in cellular fitness. Tracking of these transcripts along the temporal axis in multiple...
6.
Gupta R, Mittal A, Agrawal V, Gupta S, Gupta K, Jain R, et al.
J Biol Chem
. 2021 Jul;
297(2):100956.
PMID: 34265305
The molecular mechanisms of olfaction, or the sense of smell, are relatively underexplored compared with other sensory systems, primarily because of its underlying molecular complexity and the limited availability of...
7.
Gautam V, Mittal A, Kalra S, Mohanty S, Gupta K, Rani K, et al.
Brief Bioinform
. 2021 Jun;
22(6).
PMID: 34184038
Dramatic genomic alterations, either inducible or in a pathological state, dismantle the core regulatory networks, leading to the activation of normally silent genes. Despite possessing immense therapeutic potential, accurate detection...
8.
Gupta K, Lalit M, Biswas A, Sanada C, Greene C, Hukari K, et al.
Genome Res
. 2021 Mar;
31(4):689-697.
PMID: 33674351
Systematic delineation of complex biological systems is an ever-challenging and resource-intensive process. Single-cell transcriptomics allows us to study cell-to-cell variability in complex tissues at an unprecedented resolution. Accurate modeling of...
9.
Gupta K, Balyan K, Lamba B, Puri M, Sengupta D, Kumar M
J Matern Fetal Neonatal Med
. 2021 Feb;
35(25):5587-5594.
PMID: 33596762
Background: The placental pathological changes in hypertensive disorders of pregnancy (HDP) starts early in pregnancy, the deep convolutional neural networks (CNN) can identify these changes before its clinical manifestation. Objective:...
10.
Iyer A, Gupta K, Sharma S, Hari K, Lee Y, Ramalingam N, et al.
J Clin Med
. 2021 Jan;
10(2).
PMID: 33478182
In the published manuscript [...].