Konda Kumaraswami
Overview
Explore the profile of Konda Kumaraswami including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
108
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Recent Articles
1.
Wang X, Campbell B, Bodogai M, McDevitt R, Patrikeev A, Gusev F, et al.
Brain Behav Immun
. 2024 Aug;
122:444-455.
PMID: 39191349
Alzheimer's disease (AD) is linked to toxic Aβ plaques in the brain and activation of innate responses. Recent findings however suggest that the disease may also depend on the adaptive...
2.
Weinberger T, Denise M, Joppich M, Fischer M, Garcia Rodriguez C, Kumaraswami K, et al.
Elife
. 2024 May;
12.
PMID: 38775664
Cardiac macrophages are heterogenous in phenotype and functions, which has been associated with differences in their ontogeny. Despite extensive research, our understanding of the precise role of different subsets of...
3.
Kumaraswami K, Arnholdt C, Deindl E, Lasch M
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37629019
Increasing evidence suggests that lymphocytes play distinct roles in inflammation-induced tissue remodeling and tissue damage. Arteriogenesis describes the growth of natural bypasses from pre-existing collateral arteries. This process compensates for...
4.
Arnholdt C, Kumaraswami K, Gotz P, Kubler M, Lasch M, Deindl E
Cells
. 2022 May;
11(9).
PMID: 35563796
γδ T cells, a small subset of T cells in blood, play a substantial role in influencing immunoregulatory and inflammatory processes. The functional impact of γδ T cells on angiogenesis...
5.
Gotz P, Braumandl A, Kubler M, Kumaraswami K, Ishikawa-Ankerhold H, Lasch M, et al.
Int J Mol Sci
. 2021 Jun;
22(11).
PMID: 34071589
The complement system is a potent inflammatory trigger, activator, and chemoattractant for leukocytes, which play a crucial role in promoting angiogenesis. However, little information is available about the influence of...
6.
Kubler M, Beck S, Fischer S, Gotz P, Kumaraswami K, Ishikawa-Ankerhold H, et al.
Biomedicines
. 2021 Apr;
9(4).
PMID: 33916904
Cold-inducible RNA-binding protein (CIRP) is an intracellular RNA-chaperone and extracellular promoter of inflammation, which is increasingly expressed and released under conditions of hypoxia and cold stress. The functional relevance of...
7.
Lasch M, Kumaraswami K, Nasiscionyte S, Kircher S, van den Heuvel D, Meister S, et al.
Front Physiol
. 2020 Nov;
11:576736.
PMID: 33240100
RNase A (the bovine equivalent to human RNase 1) and RNase 5 (angiogenin) are two closely related ribonucleases. RNase 5 is described as a powerful angiogenic factor. Whether RNase A...
8.
Kumaraswami K, Salei N, Beck S, Rambichler S, Kluever A, Lasch M, et al.
Int J Mol Sci
. 2020 May;
21(10).
PMID: 32438752
Arteriogenesis, the growth of a natural bypass from pre-existing arteriolar collaterals, is an endogenous mechanism to compensate for the loss of an artery. Mechanistically, this process relies on a locally...
9.
Lasch M, Caballero Martinez A, Kumaraswami K, Ishikawa-Ankerhold H, Meister S, Deindl E
Cells
. 2020 Apr;
9(4).
PMID: 32276492
Collateral artery growth (arteriogenesis) involves the proliferation of vascular endothelial cells (ECs) and smooth muscle cells (SMCs). Whereas the proliferation of ECs is directly related to shear stress, the driving...
10.
Lasch M, Kleinert E, Meister S, Kumaraswami K, Buchheim J, Grantzow T, et al.
Blood
. 2019 Sep;
134(17):1469-1479.
PMID: 31501155
Fluid shear stress in the vasculature is the driving force for natural bypass growth, a fundamental endogenous mechanism to counteract the detrimental consequences of vascular occlusive disease, such as stroke...