Komaraiah Palle
Overview
Explore the profile of Komaraiah Palle including associated specialties, affiliations and a list of published articles.
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Articles
44
Citations
1305
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Recent Articles
1.
Khan H, Farhana F, Mostafa F, Rafiq A, Nizia E, Zabin Z, et al.
J Alzheimers Dis
. 2025 Jan;
103(3):687-705.
PMID: 39865007
Background: The prevalence of Alzheimer's disease or dementia in the elderly population has been increasing both nationally and globally. Males and females are impacted differently when it comes to cognitive...
2.
Khan H, Farhana F, Mostafa F, Rafiq A, Nizia E, Razzaq R, et al.
J Alzheimers Dis Rep
. 2024 Sep;
8(1):1133-1151.
PMID: 39247876
Background: Alzheimer's disease (AD) is related to one or more chronic illnesses, which may develop cognitive decline and dementia. Cognitive impairment is increasing, and public health officials must address risk...
3.
Acharya G, Mani C, Sah N, Saamarthy K, Young R, Reedy M, et al.
Cell Death Discov
. 2024 Jun;
10(1):278.
PMID: 38862485
Chemoresistance contributes to the majority of deaths in women with ovarian cancer (OC). Altered DNA repair and metabolic signaling is implicated in mediating therapeutic resistance. DNA damage checkpoint kinase 1...
4.
Okechukwu C, Ma X, Sah N, Mani C, Palle K, Gmeiner W
Cancers (Basel)
. 2024 Apr;
16(7).
PMID: 38611037
Combination chemotherapy regimens that include fluoropyrimidine (FP) drugs, e.g., 5-fluorouracil (5-FU), are central to the treatment of colorectal cancer liver metastases (CRLMs), a major cause of cancer mortality. We tested...
5.
Schumacher T, Gardner Z, McParlan M, Omy T, Palle K, Rumbley J, et al.
Anticancer Res
. 2024 Feb;
44(3):911-919.
PMID: 38423633
Background/aim: Telmisartan is an angiotensin II receptor type 1 (AT1) antagonist with anticancer properties against solid and hematological cancer cell lines. Using telmisartan as a template, we developed alkylamine derivatives...
6.
Mani C, Tripathi K, Chaudhary S, Somasagara R, Rocconi R, Crasto C, et al.
Neoplasia
. 2024 Feb;
50:100978.
PMID: 38401480
No abstract available.
7.
Schumacher T, Sah N, Palle K, Rumbley J, Mereddy V
Bioorg Med Chem Lett
. 2023 Aug;
93:129425.
PMID: 37557926
This work describes about the synthesis and evaluation of substituted benzofuran piperazines as potential anticancer agents. The synthesized candidates have been evaluated for their cell proliferation inhibition properties in six...
8.
Mani C, Acharya G, Saamarthy K, Ochola D, Mereddy S, Pruitt K, et al.
Breast Cancer Res
. 2023 Apr;
25(1):44.
PMID: 37081516
Background: Triple-negative breast cancer (TNBC) affects young women and is the most aggressive subtype of breast cancer (BC). TNBCs disproportionally affect women of African-American (AA) descent compared to other ethnicities....
9.
Reedy M, Jonnalagadda S, Palle K
Pathol Oncol Res
. 2022 Jan;
27:1609922.
PMID: 34987310
The human papilloma virus (HPV) high-risk variants (HPV-HR) such as HPV16 and HPV18 are responsible for most HPV related cancers, including anogenital and head and neck cancers. Here, we present...
10.
Mani C, Acharya G, Kshirsagar S, Vijayan M, Khan H, Reddy P, et al.
J Alzheimers Dis
. 2021 Nov;
85(1):207-221.
PMID: 34776453
Background: DNA damage accumulation and mitochondrial abnormalities are elevated in neurons during aging and may contribute to neurodegenerative pathologic conditions such as Alzheimer's disease. BRCA1 interacting protein 1 or BRIP1...