Kohei Sharyo
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Explore the profile of Kohei Sharyo including associated specialties, affiliations and a list of published articles.
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6
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47
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Recent Articles
1.
Hirohara S, Nishida M, Sharyo K, Obata M, Ando T, Tanihara M
Bioorg Med Chem
. 2010 Jan;
18(4):1526-35.
PMID: 20097078
In order to explore the effect of substitution patterns on the photocytotoxicity of glycoconjugated porphyrins, we synthesized and characterized a 'complete set' of tetrakis(perfluorophenyl)porphyrins having beta-d-glucopyranosylthio groups on the phenyl...
2.
Hirohara S, Obata M, Alitomo H, Sharyo K, Ando T, Tanihara M, et al.
J Photochem Photobiol B
. 2009 Aug;
97(1):22-33.
PMID: 19679489
Eight S-glycosylated 5,10,15,20-tetrakis(tetrafluorophenyl)porphyrins (1a', 1b', 1a and 1b (a: S-glucosylated, b: S-galactosylated)) and their 1,3-dipolar cycloadducts, i.e. chlorins 2a', 2b', 2a and 2b were prepared by nucleophilic substitution of the...
3.
Okitsu K, Sharyo K, Nishimura R
Langmuir
. 2009 Jun;
25(14):7786-90.
PMID: 19545140
A novel one-pot synthesis method to prepare gold nanorods was developed by using sonochemical reduction of gold ions in aqueous solution. The size of the sonochemically formed gold nanorods was...
4.
Hirohara S, Obata M, Alitomo H, Sharyo K, Ando T, Yano S, et al.
Bioconjug Chem
. 2009 Apr;
20(5):944-52.
PMID: 19378978
5,10,15,20-Tetrakis(4-(2,3,4,6-tetra-O-acetyl-beta-d-glucopyranosylthio)-2,3,5,6-tetrafluorophenyl)porphyrin 2a and its Zn(II), Pd(II), and Pt(II) complexes 2b, 2c, and 2d were prepared in excellent yields by nucleophilic substitution of the corresponding free-base porphyrin and metalloporphyrins with acetyl...
5.
Hirohara S, Obata M, Alitomo H, Sharyo K, Ogata S, Ohtsuki C, et al.
Biol Pharm Bull
. 2008 Dec;
31(12):2265-72.
PMID: 19043211
The photodynamic effect of the glycoconjugated photosensitizer library containing 16 glycoconjugated 5,10,15,20-tetraphenylporphyrins and 8 glycoconjugated 5,10,15,20-tetraphenylchlorins were examined in HeLa cells, and analyzed by two approaches, namely, physiological properties (cellular...
6.
Obata M, Hirohara S, Sharyo K, Alitomo H, Kajiwara K, Ogata S, et al.
Biochim Biophys Acta
. 2007 May;
1770(8):1204-11.
PMID: 17490818
The photocytotoxicity of four glycoconjugated porphyrins, namely 5,10,15,20-tetrakis[4-(beta-D-glucopyranosyloxy)phenyl]porphyrin (p-1a), 5,10,15,20-tetrakis[4-(beta-D-galactopyranosyloxy)phenyl]porphyrin (p-1b), 5,10,15,20-tetrakis[4-(beta-D-xylopyranosyloxy)phenyl]porphyrin (p-1c) and 5,10,15,20-tetrakis[4-(beta-D-arabinopyranosyloxy)phenyl]porphyrin (p-1d), was evaluated in HeLa cells in the concentration range from 1 to 7 microM...