Kohei Deguchi
Overview
Explore the profile of Kohei Deguchi including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
46
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Recent Articles
1.
Fujiwara Y, Miki K, Deguchi K, Naka Y, Sasaki M, Sakoda A, et al.
Stem Cell Reports
. 2023 Oct;
18(11):2108-2122.
PMID: 37802074
Engineered cardiac tissue (ECT) using human induced pluripotent stem cell-derived cardiomyocytes is a promising tool for modeling heart disease. However, tissue immaturity makes robust disease modeling difficult. Here, we established...
2.
Fujiwara Y, Deguchi K, Miki K, Nishimoto T, Yoshida Y
Methods Mol Biol
. 2021 Jul;
2320:171-180.
PMID: 34302658
Engineered cardiac tissue (ECT) derived from human induced pluripotent stem cells (iPSCs) can replicate human heart in vitro and be applied to drug discovery and heart disease models. The contraction...
3.
Miki K, Deguchi K, Nakanishi-Koakutsu M, Lucena-Cacace A, Kondo S, Fujiwara Y, et al.
Nat Commun
. 2021 Jun;
12(1):3596.
PMID: 34155205
One of the earliest maturation steps in cardiomyocytes (CMs) is the sarcomere protein isoform switch between TNNI1 and TNNI3 (fetal and neonatal/adult troponin I). Here, we generate human induced pluripotent...
4.
Yoneyama-Hirozane M, Deguchi K, Hirakawa T, Ishii T, Odani T, Matsui J, et al.
SLAS Discov
. 2017 Aug;
23(2):154-163.
PMID: 28846466
Ghrelin O-acyl transferase (GOAT; MBOAT4) catalyzes O-acylation at serine-3 of des-acyl ghrelin. Acyl ghrelin is secreted by stomach X/A-like cells and plays a role in appetite and metabolism. Therefore, GOAT...