Klaus Dembowsky
Overview
Explore the profile of Klaus Dembowsky including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
515
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wang Y, Dembowsky K, Chevalier E, Stuve P, Korf-Klingebiel M, Lochner M, et al.
Circulation
. 2019 Jan;
139(15):1798-1812.
PMID: 30696265
Background: Acute myocardial infarction (MI) elicits an inflammatory response that drives tissue repair and adverse cardiac remodeling. Inflammatory cell trafficking after MI is controlled by C-X-C motif chemokine ligand 12...
2.
Wach A, Dembowsky K, Dale G
Antimicrob Agents Chemother
. 2018 Feb;
62(4).
PMID: 29437621
Murepavadin is the first in class of the outer membrane protein-targeting antibiotics (OMPTA) and a pathogen-specific peptidomimetic antibacterial with a novel, nonlytic mechanism of action targeting Murepavadin is being developed...
3.
Gagner J, Sarfraz Y, Ortenzi V, Alotaibi F, Chiriboga L, Tayyib A, et al.
Am J Pathol
. 2017 Jul;
187(9):2080-2094.
PMID: 28734730
Resistance to antiangiogenic therapy in glioblastoma (GBM) patients may involve hypoxia-induced expression of C-X-C motif chemokine receptor 4 (CXCR4) on invading tumor cells, macrophage/microglial cells (MGCs), and glioma stem cells...
4.
Polverino E, Rosales-Mayor E, Dale G, Dembowsky K, Torres A
Chest
. 2017 Apr;
152(2):249-262.
PMID: 28442313
In many respiratory diseases characterized by an intense inflammatory response, the balance between proteolytic enzymes (proteases, including elastases) and their inhibitors (proteinases inhibitors) is not neutral. Excess activity of neutrophil...
5.
Karpova D, Ritchey J, Holt M, Abou-Ezzi G, Monlish D, Batoon L, et al.
Blood
. 2017 Apr;
129(21):2939-2949.
PMID: 28400375
Interaction between the chemokine receptor CXCR4 and its chief ligand CXCL12 plays a critical role in the retention and migration of hematopoietic stem and progenitor cells (HSPCs) in the bone...
6.
Xiang J, Hurchla M, Fontana F, Su X, Amend S, Esser A, et al.
Mol Cancer Ther
. 2015 Aug;
14(11):2473-85.
PMID: 26269605
The SDF-1 receptor CXCR4 has been associated with early metastasis and poorer prognosis in breast cancers, especially the most aggressive triple-negative subtype. In line with previous reports, we found that...
7.
Barone A, Sengupta R, Warrington N, Smith E, Wen P, Brekken R, et al.
Oncotarget
. 2014 Sep;
5(20):9811-22.
PMID: 25238146
Glioblastoma recurrence involves the persistence of a subpopulation of cells with enhanced tumor-initiating capacity (TIC) that reside within the perivascular space, or niche (PVN). Anti-angiogenic therapies may prevent the formation...
8.
Hamesch K, Subramanian P, Li X, Dembowsky K, Chevalier E, Weber C, et al.
Thromb Haemost
. 2012 Jan;
107(2):356-68.
PMID: 22234341
Impaired endothelial recovery after the implantation of drug-eluting stents is a major concern because of the increased risk for late stent thrombosis. The disruption of the chemokine axis CXCL12/CXCR4 inhibits...
9.
Nakajima H, Nakajima H, Dembowsky K, Pasumarthi K, Field L
Circ Res
. 2005 Nov;
98(1):141-8.
PMID: 16306446
MHC-TGFcys33ser transgenic mice have elevated levels of active transforming growth factor (TGF)-beta1 in the myocardium. Previous studies have shown that these animals develop atrial, but not ventricular, fibrosis. Here we...
10.
Apeler H, Peters J, Schroder W, Schneider K, Lemm G, Hinz V, et al.
Arzneimittelforschung
. 2004 Oct;
54(8):483-97.
PMID: 15460216
Aprotinin (GAS 9087-70-1) is known as a potent inhibitor of serine proteases such as trypsin, plasmin, tissue and plasma kallikrein. In this study, an aprotinin variant was designed by means...