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Kiwon Jung

Explore the profile of Kiwon Jung including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 391
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Recent Articles
1.
Lee D, Jung K, Lee J, Kang H, Lee J, Kim J, et al.
Eur J Pharmacol . 2025 Jan; 989():177272. PMID: 39809350
Obesity due to excessive body fat accumulation remains a global problem. Patients with obesity have high cortisol levels, and its dysregulation is caused by increased 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)...
2.
Kim S, You B, Bae M, Han S, Jung K, Choi Y
Pharmaceutics . 2023 Sep; 15(9). PMID: 37765246
Mirabegron (MBR) is a β-adrenoceptor agonist used for treating overactive bladder syndrome. Due to its poor solubility and low bioavailability (), the development of novel MBR formulations has garnered increasing...
3.
Yu J, You B, Bae M, Han S, Jung K, Choi Y
Pharmaceutics . 2023 Aug; 15(8). PMID: 37631381
Febuxostat (FBX), a selective xanthine oxidase inhibitor, belongs to BCS class II, showing low solubility and high permeability with a moderate value (<49%). Recently, FBX/L-pyroglutamic acid cocrystal (FBX-PG) was developed...
4.
You B, Bae M, Han S, Jung J, Jung K, Choi Y
Pharmaceutics . 2023 May; 15(5). PMID: 37242634
Tenofovir (TEV) is a nucleotide reverse transcriptase inhibitor used against human immunodeficiency virus (HIV) reverse transcriptase. To improve the poor bioavailability of TEV, TEV disoproxil (TD), an ester prodrug of...
5.
Lee D, Hong S, Jung K, Choi S, Kang K
Plants (Basel) . 2022 Dec; 11(24). PMID: 36559664
The suppressive effects of flavonoids on macrophage-associated adipocyte inflammation in a differentiated murine preadipocyte cell line (3T3-L1) co-cultured with a murine macrophage cell line (RAW264.7) were evaluated. Extracellular lipid accumulation...
6.
Bang Y, Kwon Y, Kim M, Moon S, Jung K, Choi H
Acta Pharmacol Sin . 2022 Sep; 44(4):752-765. PMID: 36138143
Protein aggregation and the abnormal accumulation of aggregates are considered as common mechanisms of neurodegeneration such as Parkinson's disease (PD). Ursolic acid (UA), a natural pentacyclic triterpenoid compound, has shown...
7.
Kiyonga A, Park G, Kim H, Suh Y, Kim T, Jung K
Molecules . 2021 Nov; 26(21). PMID: 34770966
Ionic liquids (ILs) have attracted significant interest because of their desirable properties. These characteristics have improved their application to overcome the shortcomings of conventional separation techniques for phytochemicals. In this...
8.
Phung H, Lee S, Hong S, Lee S, Jung K, Kang K
Antioxidants (Basel) . 2021 Oct; 10(10). PMID: 34679744
Similar to other organs, the skin undergoes a natural aging process. Moreover, constant direct exposure to environmental stresses, including ultraviolet irradiation, causes the signs of skin aging to appear rather...
9.
Lee J, Park M, Jung K, Hong G, Lee H, Kim D, et al.
Bioorg Med Chem Lett . 2021 Apr; 41:128012. PMID: 33838305
Tacrolimus (FK506), a calcineurin inhibitor, is an effective immunosuppressive agent mainly used to lower the risk of organ rejection after allogeneic organ transplant. However, FK506-associated adverse effects, such as nephrotoxicity,...
10.
Lee S, Kwon N, Seo B, Lee J, Cho H, Kim K, et al.
Eur J Med Chem . 2021 Apr; 218:113405. PMID: 33831781
Recently, non-canonical roles of Lysyl-tRNA Synthetase (KRS), which is associated with cell migration and cancer metastasis, have been reported. Therefore, KRS has emerged as a promising target for the treatment...