Kirsi Vaaralahti
Overview
Explore the profile of Kirsi Vaaralahti including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
33
Citations
387
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pulli K, Saarimaki-Vire J, Ahonen P, Liu X, Ibrahim H, Chandra V, et al.
JCI Insight
. 2024 May;
9(10).
PMID: 38775154
MAPK activating death domain (MADD) is a multifunctional protein regulating small GTPases RAB3 and RAB27, MAPK signaling, and cell survival. Polymorphisms in the MADD locus are associated with glycemic traits,...
2.
Eskici N, Madhusudan S, Vaaralahti K, Yellapragada V, Gomez-Sanchez C, Karkinen J, et al.
Eur J Endocrinol
. 2023 Aug;
189(2):271-280.
PMID: 37619992
Objective: Congenital hypogonadotropic hypogonadism (CHH) is a rare, genetically heterogeneous reproductive disorder caused by gonadotropin-releasing hormone (GnRH) deficiency. Approximately half of CHH patients also have decreased or absent sense of...
3.
Wang Y, Madhusudan S, Cotellessa L, Kvist J, Eskici N, Yellapragada V, et al.
Stem Cells
. 2022 Sep;
40(12):1107-1121.
PMID: 36153707
Hypothalamic gonadotropin-releasing hormone (GnRH) neurons lay the foundation for human development and reproduction; however, the critical cell populations and the entangled mechanisms underlying the development of human GnRH neurons remain...
4.
Hietamaki J, Karkinen J, Iivonen A, Vaaralahti K, Tarkkanen A, Almusa H, et al.
EClinicalMedicine
. 2022 Jul;
51:101556.
PMID: 35875813
Background: Childhood-onset combined pituitary hormone deficiency (CPHD) has a wide spectrum of etiologies and genetic causes for congenital disease. We aimed to describe the clinical spectrum and genetic etiologies of...
5.
Yellapragada V, Eskici N, Wang Y, Madhusudan S, Vaaralahti K, Tuuri T, et al.
Dis Model Mech
. 2022 Jul;
15(8).
PMID: 35833364
Fibroblast growth factor 8 (FGF8), acting through the fibroblast growth factor receptor 1 (FGFR1), has an important role in the development of gonadotropin-releasing hormone-expressing neurons (GnRH neurons). We hypothesized that...
6.
Varimo T, Miettinen P, Vaaralahti K, Toppari J, Huopio H, Voutilainen R, et al.
J Endocr Soc
. 2022 Feb;
6(3):bvac013.
PMID: 35187383
Context: Circulating levels of liver-enriched antimicrobial peptide 2 (LEAP2), a ghrelin receptor antagonist, decrease under caloric restriction and increase in obesity. The role of LEAP2 in male puberty, a phase...
7.
Iivonen A, Karkinen J, Yellapragada V, Sidoroff V, Almusa H, Vaaralahti K, et al.
Eur J Endocrinol
. 2021 Apr;
185(1):57-66.
PMID: 33909591
Patients with deletions on chromosome 9q31.2 may exhibit delayed puberty, craniofacial phenotype including cleft lip/palate, and olfactory bulb hypoplasia. We report a patient with congenital HH with anosmia (Kallmann syndrome,...
8.
Varimo T, Wang Y, Miettinen P, Vaaralahti K, Hero M, Raivio T
Eur J Endocrinol
. 2021 Mar;
184(5):K11-K14.
PMID: 33667194
Objective: The role of miRNA as endocrine regulators is emerging, and microRNA mir-30b has been reported to repress Mkrn3. However, the expression of miR-30b during male puberty has not been...
9.
Varimo T, Iivonen A, Kansakoski J, Wehkalampi K, Hero M, Vaaralahti K, et al.
Pediatr Res
. 2020 Nov;
90(2):431-435.
PMID: 33214675
Background: Paternally inherited loss-of-function mutations in MKRN3 underlie central precocious puberty (CPP). We describe clinical and genetic features of CPP patients with paternally inherited MKRN3 mutations in two independent families....
10.
Hietamaki J, Gregory L, Ayoub S, Iivonen A, Vaaralahti K, Liu X, et al.
J Clin Endocrinol Metab
. 2020 Feb;
105(6).
PMID: 32060556
Context: Congenital pituitary hormone deficiencies with syndromic phenotypes and/or familial occurrence suggest genetic hypopituitarism; however, in many such patients the underlying molecular basis of the disease remains unknown. Objective: To...