Kip P Conner
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Explore the profile of Kip P Conner including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
144
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0
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Recent Articles
11.
Conner K, Rock B, Kwon G, Balthasar J, Abuqayyas L, Wienkers L, et al.
Drug Metab Dispos
. 2014 Sep;
42(11):1906-13.
PMID: 25209366
The pharmacokinetic (PK) behavior of monoclonal antibodies (mAbs) is influenced by target-mediated drug disposition, off-target effects, antidrug antibody-mediated clearance, and interaction with fragment-crystallizable domain (Fc) receptors such as neonatal Fc...
12.
Conner K, Schimpf A, Cruce A, McLean K, Munro A, Frank D, et al.
Biochemistry
. 2014 Mar;
53(9):1428-34.
PMID: 24576089
The heme-containing cytochrome P450s exhibit isoform-dependent ferric spin equilibria in the resting state and differential substrate-dependent spin equilibria. The basis for these differences is not well understood. Here, magnetic circular...
13.
Conner K, Vennam P, Woods C, Krzyaniak M, Bowman M, Atkins W
Biochemistry
. 2012 Jul;
51(32):6441-57.
PMID: 22809252
In comparison to imidazole (IMZ) and 1,2,4-triazole (1,2,4-TRZ), the isosteric 1,2,3-triazole (1,2,3-TRZ) is unrepresented among cytochrome P450 (CYP) inhibitors. This is surprising because 1,2,3-TRZs are easily obtained via "click" chemistry....
14.
Conner K, Woods C, Atkins W
Arch Biochem Biophys
. 2010 Oct;
507(1):56-65.
PMID: 20939998
Cytochrome P450s (CYPs) are heme-containing monooxygenases that contribute to an enormous range of enzymatic function including biosynthetic and detoxification roles. This review summarizes recent studies concerning interactions of CYPs with...
15.
Shireman L, Kripps K, Balogh L, Conner K, Whittington D, Atkins W
Arch Biochem Biophys
. 2010 Sep;
504(2):182-9.
PMID: 20836986
4-Hydroxy-2-trans-nonenal (HNE) is a lipid peroxidation product that contributes to the pathophysiology of several diseases with components of oxidative stress. The electrophilic nature of HNE results in covalent adduct formation...