Kine M K Sand
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Explore the profile of Kine M K Sand including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
304
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Recent Articles
1.
Merten H, Brandl F, Zimmermann M, Schaefer J, Irpinio L, Sand K, et al.
Eur J Pharm Biopharm
. 2021 Jul;
167:104-113.
PMID: 34303832
Serum albumin shows slow clearance from circulation due to neonatal Fc receptor (FcRn)-mediated recycling and has been used for half-life extension. We report here fusions to a high-affinity DARPin, binding...
2.
Bern M, Nilsen J, Ferrarese M, Sand K, Gjolberg T, Lode H, et al.
Sci Transl Med
. 2020 Oct;
12(565).
PMID: 33055243
Needle-free uptake across mucosal barriers is a preferred route for delivery of biologics, but the efficiency of unassisted transmucosal transport is poor. To make administration and therapy efficient and convenient,...
3.
Hubbard J, Pyzik M, Rath T, Kozicky L, Sand K, Gandhi A, et al.
J Exp Med
. 2020 Jul;
217(10).
PMID: 32658257
IgG immune complexes (ICs) promote autoimmunity through binding fragment crystallizable (Fc) γ-receptors (FcγRs). Of these, the highly prevalent FcγRIIa (CD32a) histidine (H)-131 variant (CD32aH) is strongly linked to human autoimmune...
4.
Pyzik M, Sand K, Hubbard J, Andersen J, Sandlie I, Blumberg R
Front Immunol
. 2019 Jul;
10:1540.
PMID: 31354709
Antibodies are essential components of an adaptive immune response. Immunoglobulin G (IgG) is the most common type of antibody found in circulation and extracellular fluids. Although IgG alone can directly...
5.
Grevys A, Nilsen J, Sand K, Daba M, Oynebraten I, Bern M, et al.
Nat Commun
. 2018 Feb;
9(1):621.
PMID: 29434196
Albumin and IgG have remarkably long serum half-lives due to pH-dependent FcRn-mediated cellular recycling that rescues both ligands from intracellular degradation. Furthermore, increase in half-lives of IgG and albumin-based therapeutics...
6.
Walchli S, Kumari S, Fallang L, Sand K, Yang W, Landsverk O, et al.
Eur J Immunol
. 2013 Dec;
44(3):774-84.
PMID: 24293164
Protective T-cell responses depend on efficient presentation of antigen (Ag) in the context of major histocompatibility complex class I (MHCI) and class II (MHCII) molecules. Invariant chain (Ii) serves as...