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Kim Wong

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Articles 59
Citations 5747
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Recent Articles
1.
Arends M, Del Castillo Velasco-Herrera M, Cheema S, Wong K, Boccacino J, Vermes I, et al.
Br J Dermatol . 2024 Nov; PMID: 39546556
No abstract available.
2.
van der Weyden L, Del Castillo Velasco-Herrera M, Cheema S, Wong K, Boccacino J, Vermes I, et al.
Br J Dermatol . 2024 Nov; 192(3):551-553. PMID: 39506538
No abstract available.
3.
van der Weyden L, Del Castillo Velasco-Herrera M, Cheema S, Wong K, Boccacino J, Offord V, et al.
Br J Dermatol . 2024 Oct; 192(2):335-343. PMID: 39392932
Background: Cutaneous leiomyosarcoma (cLMS) is a rare soft-tissue neoplasm, showing smooth muscle differentiation, that arises from the mesenchymal cells of the dermis. To date, genetic investigation of these tumours has...
4.
Wong K, Abascal F, Ludwig L, Aupperle-Lellbach H, Grassinger J, Wright C, et al.
Genome Biol . 2023 Aug; 24(1):191. PMID: 37635261
Background: In humans, muscle-invasive bladder cancer (MIBC) is highly aggressive and associated with a poor prognosis. With a high mutation load and large number of altered genes, strategies to delineate...
5.
Valcarcel-Jimenez L, Rogerson C, Yong C, Schmidt C, Yang M, Cremades-Rodelgo M, et al.
Sci Adv . 2022 Oct; 8(42):eabq8297. PMID: 36269833
Fumarate hydratase (FH) is a mitochondrial enzyme that catalyzes the reversible hydration of fumarate to malate in the tricarboxylic acid (TCA) cycle. Germline mutations of lead to hereditary leiomyomatosis and...
6.
Lewitus E, Sanders-Buell E, Bose M, OSullivan A, Poltavee K, Li Y, et al.
Virus Evol . 2021 Sep; 7(2):veab057. PMID: 34532060
The scale of the HIV-1 epidemic underscores the need for a vaccine. The multitude of circulating HIV-1 strains together with HIV-1's high evolvability hints that HIV-1 could adapt to a...
7.
Wong K, Ludwig L, Krijgsman O, Adams D, Wood G, van der Weyden L
Dis Model Mech . 2021 Jul; 14(7). PMID: 34296746
Angiosarcoma (AS) is a highly aggressive tumor of blood and lymphatic vessels in humans that shares many similarities with spontaneously occurring hemangiosarcoma (HSA) in dogs and cats. To investigate the...
8.
Tombocon O, Tregaskis P, Reid C, Chiappetta D, Fallon K, Jackson S, et al.
Int J Qual Health Care . 2021 Jul; 33(3). PMID: 34282840
Background: Despite evidence that clinical outcomes for patients treated with peritoneal dialysis (PD) or home haemodialysis are better than for patients treated with conventional satellite or hospital-based haemodialysis, rates of...
9.
Ferreira I, Droop A, Edwards O, Wong K, Harle V, Habeeb O, et al.
Mod Pathol . 2021 Jun; 34(11):2009-2019. PMID: 34155350
Dedifferentiation and transdifferentiation are rare and only poorly understood phenomena in cutaneous melanoma. To study this disease more comprehensively we have retrieved 11 primary cutaneous melanomas from our pathology archives...
10.
Supper E, Rudat S, Iyer V, Droop A, Wong K, Spinella J, et al.
Nat Commun . 2021 May; 12(1):2482. PMID: 33931647
While oncogenes promote tumorigenesis, they also induce deleterious cellular stresses, such as apoptosis, that cancer cells must combat by coopting adaptive responses. Whether tumor suppressor gene haploinsufficiency leads to such...