Kim Lee Chua
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Explore the profile of Kim Lee Chua including associated specialties, affiliations and a list of published articles.
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21
Citations
575
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Recent Articles
1.
Wang R, Chua K, Neoh K
ACS Biomater Sci Eng
. 2021 Jan;
1(6):405-415.
PMID: 33445245
Bacterial colonization by nosocomial pathogens on medical device surface can cause serious and life-threatening infections. We showed that 4-amide-piperidine-C12 (4AP12), the base form of 4-dodecaneamidepiperidine HCl, has broad-spectrum antimicrobial activity...
2.
Li M, Kang E, Chua K, Neoh K
Biomater Sci
. 2019 May;
7(7):2961-2974.
PMID: 31099344
Bacterial biofilms cause chronic infections due to their inherent tolerance to antimicrobial therapies. We describe and compare the efficacy of two types of sugar (d-glucose and d-mannose)-modified cyclodextrin nanocarriers (CD-GLU...
3.
Richmond G, Evans L, Anderson M, Wand M, Bonney L, Ivens A, et al.
mBio
. 2016 Jun;
7(3).
PMID: 27329755
No abstract available.
4.
Richmond G, Evans L, Anderson M, Wand M, Bonney L, Ivens A, et al.
mBio
. 2016 Apr;
7(2):e00430-16.
PMID: 27094331
The opportunistic pathogen Acinetobacter baumannii is able to persist in the environment and is often multidrug resistant (MDR), causing difficulties in the treatment of infections. Here, we show that the...
5.
Li M, Neoh K, Xu L, Yuan L, Leong D, Kang E, et al.
Pharm Res
. 2016 Jan;
33(5):1161-74.
PMID: 26792570
Purpose: The use of "Trojan Horse" nanocarriers for antibiotics to enhance the activity of antibiotics against susceptible and resistant bacteria is investigated. Methods: Antibiotic carriers (CD-MAN and CD-GLU) are prepared...
6.
Chow J, Yang Y, Tay S, Chua K, Yew W
Antimicrob Agents Chemother
. 2014 Jan;
58(3):1802-5.
PMID: 24379199
Acinetobacter baumannii is a major human pathogen associated with multidrug-resistant nosocomial infections; its virulence is attributed to quorum-sensing-mediated biofilm formation, and disruption of biofilm formation is an attractive antivirulence strategy....
7.
Amin I, Richmond G, Sen P, Koh T, Piddock L, Chua K
BMC Microbiol
. 2013 Jul;
13:158.
PMID: 23848834
Background: Acinetobacter baumannii is an important nosocomial pathogen that has become increasingly resistant to multiple antibiotics. Genetic manipulation of MDR A. baumannii is useful especially for defining the contribution of...
8.
Yang Y, Chua K
Int J Antimicrob Agents
. 2013 Jul;
42(3):283-4.
PMID: 23837925
No abstract available.
9.
Gamage A, Shui G, Wenk M, Chua K
Microbiology (Reading)
. 2011 Jan;
157(Pt 4):1176-1186.
PMID: 21252275
The genome of Burkholderia pseudomallei encodes three acylhomoserine lactone (AHL) quorum sensing systems, each comprising an AHL synthase and a signal receptor/regulator. The BpsI-BpsR system produces N-octanoylhomoserine lactone (C8HL) and...
10.
Ching S, Tan W, Chua K, Lam Y
Bioorg Med Chem
. 2010 Aug;
18(18):6657-65.
PMID: 20797869
Five analogs of cyclic di-nucleotidic acid including c-di-GMP were synthesized and evaluated for their biological activities on Slr1143, a diguanylate cyclase of Synechocystis sp. Slr1143 was overexpressed from the recombinant...