Kilian Bartholome
Overview
Explore the profile of Kilian Bartholome including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
304
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0
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Recent Articles
1.
Christopoulos P, Pfeifer D, Bartholome K, Follo M, Timmer J, Fisch P, et al.
Blood
. 2011 Jan;
117(14):3836-46.
PMID: 21270444
Epidemiologic data show that the immune system may control or promote the emergence and growth of neoplastic lymphomatous clones. Conversely, systemic lymphomas, especially myeloma and chronic lymphocytic leukemia (CLL), are...
2.
Bartholome K, Kreutz C, Timmer J
J Comput Biol
. 2009 Jul;
16(7):959-67.
PMID: 19580524
In order to handle and interpret the vast amounts of data produced by microarray experiments, the analysis of sets of genes with a common biological functionality has been shown to...
3.
Buchner M, Fuchs S, Prinz G, Pfeifer D, Bartholome K, Burger M, et al.
Cancer Res
. 2009 Jun;
69(13):5424-32.
PMID: 19549911
B-cell receptor signaling contributes to apoptosis resistance in chronic lymphocytic leukemia (CLL), limiting the efficacy of current therapeutic approaches. In this study, we investigated the expression of spleen tyrosine kinase...
4.
Wiech T, Nikolopoulos E, Weis R, Langer R, Bartholome K, Timmer J, et al.
Lab Invest
. 2008 Jul;
89(4):385-97.
PMID: 18663352
We performed genome-wide analysis of copy-number changes and loss of heterozygosity (LOH) in Barrett's esophageal adenocarcinoma by single nucleotide polymorphism (SNP) microarrays to identify associated genomic alterations. DNA from 27...
5.
Bartholome K, Rius M, Letschert K, Keller D, Timmer J, Keppler D
Drug Metab Dispos
. 2007 Jun;
35(9):1476-81.
PMID: 17548463
Vectorial transport of endogenous small molecules, toxins, and drugs across polarized epithelial cells contributes to their half-life in the organism and to detoxification. To study vectorial transport in a quantitative...
6.
Kollmann M, Lovdok L, Bartholome K, Timmer J, Sourjik V
Nature
. 2005 Nov;
438(7067):504-7.
PMID: 16306993
Cellular biochemical networks have to function in a noisy environment using imperfect components. In particular, networks involved in gene regulation or signal transduction allow only for small output tolerances, and...