Kikuo Onozaki
Overview
Explore the profile of Kikuo Onozaki including associated specialties, affiliations and a list of published articles.
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Articles
65
Citations
1228
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Recent Articles
1.
Ogata A, Hayashi K, Kitano T, Onozaki K, Itoh S, Hida S
Biochem Biophys Res Commun
. 2022 Oct;
632:107-112.
PMID: 36206594
Basophils are known to produce a large amount of IL-4 in response to stimuli and play a role in the initiation and propagation of type 2 inflammations. S. aureus secretes...
2.
Taniguchi K, Hayashi D, Yasuda N, Nakayama M, Yazawa K, Ogawa S, et al.
mSphere
. 2021 Mar;
6(2).
PMID: 33692195
Genomic analysis revealed that the vaccine seed lot of bacillus Calmette-Guérin (BCG) Tokyo 172 contains two subclones (types I and II), but their phenotypic differences have not been elucidated. In...
3.
Nishiyama S, Urabe A, Morikawa A, Kobayashi M, Onozaki K, Itoh S, et al.
Biochem Biophys Res Commun
. 2020 Aug;
532(2):200-204.
PMID: 32859377
S. aureus is associated with atopic dermatitis (AD). Several staphylococcal products including cell wall components, protease, and exotoxins, are thought to be involved in allergic inflammation of AD via activating...
4.
Kobayashi M, Kitano T, Nishiyama S, Sanjo H, Onozaki K, Taki S, et al.
Biochem Biophys Res Commun
. 2019 Feb;
511(2):350-355.
PMID: 30795864
Staphylococcal superantigen-like (SSL) protein is a family of exotoxins that consists of 14 SSLs, and the roles of several SSLs in immune evasion of the cocci have been revealed. However...
5.
Hayashi K, Itoh S, Morikawa A, Onozaki K, Taki S, Tsuji T, et al.
Biochem Biophys Res Commun
. 2018 Dec;
508(1):263-269.
PMID: 30497774
Staphylococcal α-hemolysin (Hla) is a principal small β-barrel pore forming toxin. It targets a variety of mammalian cells including immune cells; however little is known about its effects on mast...
6.
Takeno M, Kitagawa S, Yamanaka J, Teramoto M, Tomita H, Shirai N, et al.
Biol Pharm Bull
. 2018 Jun;
41(6):877-884.
PMID: 29863076
The risk of rheumatoid arthritis (RA) is linked to environmental and genetic factors. Cigarette smoking is an established environmental risk factor for the disease that contributes to its development and...
7.
Kohno K, Itoh S, Hanai A, Takii T, Fujiwara T, Onozaki K, et al.
Biochem Biophys Res Commun
. 2018 Feb;
497(2):713-718.
PMID: 29462623
Staphylococcal superantigen like 5 (SSL5) is an exotoxin produced by S. aureus and has a strong inhibitory effect on MMP-9 enzymatic activity. However, the mechanism of inhibition remains unclear. We...
8.
Matsumura T, Hayashi H, Takii T, Thorn C, Whitehead A, Inoue J, et al.
J Leukoc Biol
. 2018 Jan;
75(6):1056-1061.
PMID: 29350829
We have previously reported that the proinflammatory cytokine interleukin (IL)-1α can up-regulate functional Toll-like receptor 2 (TLR2) expression in primary-cultured murine hepatocytes, and bacterial lipopeptide (BLP) is capable of signaling...
9.
Itoh S, Takii T, Onozaki K, Tsuji T, Hida S
Biochem Biophys Res Commun
. 2017 Feb;
485(1):201-208.
PMID: 28193526
Staphylococcal superantigen-like proteins (SSLs) are a family of exoproteins of Staphylococcus aureus. We have shown that SSL10 binds to vitamin K-dependent coagulation factors and inhibits blood coagulation induced by recalcification...
10.
Taniguchi K, Miyatake Y, Hayashi D, Takami A, Itoh S, Yamamoto S, et al.
Microbiol Immunol
. 2015 Sep;
59(11):684-9.
PMID: 26399380
Interleukin-12 is one of the cytokines that induce acquired immunity by progressing the differentiation of T cells. When antigens are presented by APCs, including macrophages and DCs, T cells are...