Khurum H Khan
Overview
Explore the profile of Khurum H Khan including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
365
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0
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Recent Articles
1.
Puglisi M, Molife L, de Jonge M, Khan K, van Doorn L, Forster M, et al.
Future Oncol
. 2021 Apr;
17(21):2747-2758.
PMID: 33849298
This Phase I study investigated safety of navitoclax and docetaxel in patients (n = 41) with advanced solid tumors. Two navitoclax plus docetaxel dosing schedules (21 and 28 days) were...
2.
Anandappa G, Lampis A, Cunningham D, Khan K, Kouvelakis K, Vlachogiannis G, et al.
Clin Cancer Res
. 2019 Apr;
25(13):3830-3838.
PMID: 30952636
Purpose: Anti-EGFR mAbs are effective in the treatment of metastatic colorectal cancer (mCRC) patients. status and tumor location (sidedness) are predictive markers of patients' response to anti-EGFR mAbs. Recently, low...
3.
Khan K, Cunningham D, Werner B, Vlachogiannis G, Spiteri I, Heide T, et al.
Cancer Discov
. 2018 Sep;
8(10):1270-1285.
PMID: 30166348
Sequential profiling of plasma cell-free DNA (cfDNA) holds immense promise for early detection of patient progression. However, how to exploit the predictive power of cfDNA as a liquid biopsy in...
4.
Khan K, Wong M, Rihawi K, Bodla S, Morganstein D, Banerji U, et al.
Oncologist
. 2016 May;
21(7):855-60.
PMID: 27151652
Background: Dysregulation of the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) pathway is implicated in human cancer growth and progression. Agents targeting this pathway are associated with hyperglycemia due...
5.
Khan K, Blanco-Codesido M, Molife L
Crit Rev Oncol Hematol
. 2014 Feb;
90(3):200-19.
PMID: 24507955
Apoptosis, a physiological process of programmed cell death, is disrupted in various malignancies. It has been exploited as an anti-cancer strategy traditionally by inducing DNA damage with chemotherapy and radiotherapy....
6.
Khan K, Yap T, Yan L, Cunningham D
Chin J Cancer
. 2013 May;
32(5):253-65.
PMID: 23642907
The phosphoinositide 3-kinase-AKT-mammalian target of rapamycin (PI3K-AKT-mTOR) pathway is a frequently hyperactivated pathway in cancer and is important for tumor cell growth and survival. The development of targeted therapies against...
7.
Khan K, Fenton A, Murtagh E, McAleer J, Clayton A
Tumori
. 2012 Dec;
98(5):139e-142e.
PMID: 23235770
Sunitinib is one of the standard targeted therapies used in metastatic renal cell carcinoma. It is generally a reasonably tolerated oral systemic therapy but can be occasionally associated with life-threatening...
8.
Khan K, Goody R, Hameed H, Jalil A, Coyle V, McAleer J
Tumori
. 2012 Dec;
98(5):575-80.
PMID: 23235751
Aims And Background: . The incidence of malignant melanoma has risen steadily over recent decades. NCI data from 2005-2007 have suggested that 1.93% of individuals born today in the US...
9.
Shirmeen A, Khan M, Khan K, Khan K
Ulster Med J
. 2007 Sep;
76(3):144-5.
PMID: 17853640
Aims: To investigate the impact of fertility control efforts on reducing fertility and to study the contributory role of fertility inhibiting factors viz, age of the marriage, breast feeding and...