Khanh Tran
Overview
Explore the profile of Khanh Tran including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
148
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0
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Recent Articles
11.
Planken S, Behenna D, Nair S, Johnson T, Nagata A, Almaden C, et al.
J Med Chem
. 2017 Mar;
60(7):3002-3019.
PMID: 28287730
Mutant epidermal growth factor receptor (EGFR) is a major driver of non-small-cell lung cancer (NSCLC). Marketed first generation inhibitors, such as erlotinib, effect a transient beneficial response in EGFR mutant...
12.
Cheng H, Nair S, Murray B, Almaden C, Bailey S, Baxi S, et al.
J Med Chem
. 2016 Jan;
59(5):2005-24.
PMID: 26756222
First generation EGFR TKIs (gefitinib, erlotinib) provide significant clinical benefit for NSCLC cancer patients with oncogenic EGFR mutations. Ultimately, these patients' disease progresses, often driven by a second-site mutation in...
13.
Fajardo V, Bombardier E, Tran K, Metherel A, Irvine T, Holloway G, et al.
J Membr Biol
. 2015 Jul;
248(6):1089-96.
PMID: 26193810
In a previous study, we reported lower sarcoplasmic reticulum (SR) Ca(2+) pump ionophore ratios in rat soleus compared to red and white gastrocnemius (RG, WG) muscles which may be indicative...
14.
Fajardo V, Bombardier E, McMillan E, Tran K, Wadsworth B, Gamu D, et al.
Dis Model Mech
. 2015 Jun;
8(8):999-1009.
PMID: 26035394
Centronuclear myopathy (CNM) is a congenital myopathy that is histopathologically characterized by centrally located nuclei, central aggregation of oxidative activity, and type I fiber predominance and hypotrophy. Here, we obtained...
15.
Murphy S, Alton G, Bailey S, Baxi S, Burke B, Chappie T, et al.
J Med Chem
. 2011 Nov;
54(24):8490-500.
PMID: 22040023
Analogues substituted with various amines at the 6-position of the pyrazine ring on (4-amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrazin-2-ylmethanone were discovered as potent and selective inhibitors of PDK1 with potential as anticancer agents. An early...
16.
Tran K, Levin R, Mousa S
Adv Urol
. 2009 Dec;
:345324.
PMID: 20029638
Overactive bladder syndrome (OAB) refers to individuals with the following symptoms: urinary urgency, increased urinary frequency, and urge incontinence. These symptoms are not life threatening but can cause embarrassment and...