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Khanh K Nguyen

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Recent Articles
1.
Ishchenko Y, Jeng A, Feng S, Nottoli T, Manriquez-Rodriguez C, Nguyen K, et al.
bioRxiv . 2024 Aug; PMID: 39131289
Genetic variants in TRIO are associated with neurodevelopmental disorders (NDDs) including schizophrenia (SCZ), autism spectrum disorder (ASD) and intellectual disability. TRIO uses its two guanine nucleotide exchange factor (GEF) domains...
2.
Perez H, Pannu J, Frank E, Adebowale A, Hebert S, Watson W, et al.
Otolaryngol Head Neck Surg . 2024 Jun; 171(5):1426-1432. PMID: 38943454
Objective: To evaluate patients' satisfaction with opioid versus opioid-sparing postoperative analgesia in patients undergoing outpatient head and neck surgery. Study Design: Prospective randomized trial. Setting: Tertiary care academic hospital. Methods:...
3.
Viet C, Asam K, Yu G, Dyer E, Kochanny S, Thomas C, et al.
NPJ Precis Oncol . 2024 Jun; 8(1):130. PMID: 38851780
Oral squamous cell carcinoma (OSCC) biomarker studies rarely employ multi-omic biomarker strategies and pertinent clinicopathologic characteristics to predict mortality. In this study we determine for the first time a combined...
4.
Espinoza M, Nguyen K, Sycks M, Lyu Z, Quanrud G, Montoya M, et al.
J Biol Chem . 2022 Oct; 298(12):102597. PMID: 36244454
Most eukaryotic secretory proteins are cotranslationally translocated through Sec61 into the endoplasmic reticulum (ER). Because these proteins have evolved to fold in the ER, their mistargeting is associated with toxicity....
5.
Trinh L, Vinh M, Choudhary A, Levitt B, Kutty G, Shieh E, et al.
Medicine (Baltimore) . 2022 Sep; 101(37):e30577. PMID: 36123845
Endoscopic screening is used widely to minimize the rates of colorectal cancer cases and deaths. During highly virulent infectious disease pandemics such as the coronavirus disease 2019 (COVID-19) pandemic, it...
6.
Lyu Z, Sycks M, Espinoza M, Nguyen K, Montoya M, Galapate C, et al.
ACS Chem Biol . 2022 Jun; 17(7):1963-1977. PMID: 35675579
The proper trafficking of eukaryotic proteins is essential to cellular function. Genetic, environmental, and other stresses can induce protein mistargeting and, in turn, threaten cellular protein homeostasis. Current methods for...
7.
Zinn A, Izadjoo M, Kim H, Brody R, Roth R, Vega A, et al.
Front Cell Infect Microbiol . 2022 Jan; 11:752899. PMID: 34976853
The continued proliferation of superbugs in hospitals and the coronavirus disease 2019 (COVID-19) has created an acute worldwide demand for sustained broadband pathogen suppression in households, hospitals, and public spaces....
8.
Seaman A, Seligman K, Nguyen K, Al-Qurayshi Z, Kendell N, Pagedar N
Cancer . 2021 Aug; 128(1):192-202. PMID: 34460935
Background: Little is known about cancer survivors who discontinue survivorship care. The objective of this study was to characterize patients with head and neck cancer who discontinue survivorship care with...
9.
Nguyen K, Thurmond S, Hai R, Genereux J
Anal Bioanal Chem . 2019 Jun; 411(19):4987-4998. PMID: 31254054
Influenza infection requires viral escape from early endosomes into the cytosol, which is enabled by an acid-induced irreversible conformational transformation in the viral protein hemagglutinin. Despite the direct relationship between...
10.
Nguyen K, Liu Y, Chang C, Park J, Kim C, Hondorp B, et al.
Otolaryngol Head Neck Surg . 2019 Mar; 160(5):839-846. PMID: 30832548
Objective: To compare the efficacy of pain control and opioid consumption between patients who receive opioid as primary analgesic therapy and those who receive ibuprofen. Study Design: Prospective randomized trial....